Biotransformation of some steroids by Mucor hiemalis MRC 70325

Yıldırım, Kudret; Kuru, Ali

dc.contributor.authors	Yildirim, K; Saran, H; Dolu, OF; Kuru, A;
dc.date.accessioned	2020-02-24T14:16:06Z
dc.date.available	2020-02-24T14:16:06Z
dc.date.issued	2013
dc.identifier.citation	Yildirim, K; Saran, H; Dolu, OF; Kuru, A; (2013). Biotransformation of some steroids by Mucor hiemalis MRC 70325. JOURNAL OF CHEMICAL RESEARCH, , 569-566
dc.identifier.issn	1747-5198
dc.identifier.uri	https://doi.org/10.3184/174751913X13745069090242
dc.identifier.uri	https://hdl.handle.net/20.500.12619/44947
dc.description.abstract	In this work, incubations of testosterone, dehydroepiandrosterone and pregnenolone with Mucor hiemalis MRC 70325 have been reported. Incubation of testosterone afforded androst-4-en-3,17-dione (3%), 14 alpha-hydroxyandrost-4- en-3,17-dione (9%), 6 beta-hydroxyandrost-4-en-3,17-dione (2%) and 14 alpha, 17 beta-dihydroxyandrost-4-en-3-one (62%). Incubation of dehydroepiandrosterone afforded 3 beta, 17 beta-dihydroxyandrost-5-ene (6%) and 3 beta, 7 alpha-dihydroxyandrost-5-en- 17-one (72%). Incubation of pregnenolone afforded 3 beta, 14 alpha-dihydroxypregn-5-en-7,20-dione (3%), 3 beta, 7 alpha-dihydroxy-pregn-5-en-20-one (64%) and 3 beta, 7 alpha, 11 alpha-trihydroxypregn-5-en-20-one (11%). 3 beta, 14 alpha-Dihydroxypregn-5-en-7,20-dione was identified as a new metabolite.
dc.language	English
dc.publisher	SAGE PUBLICATIONS LTD
dc.subject	Chemistry
dc.title	Biotransformation of some steroids by Mucor hiemalis MRC 70325
dc.type	Article
dc.identifier.startpage	566
dc.identifier.endpage	569
dc.contributor.department	Sakarya Üniversitesi/Fen-Edebiyat Fakültesi/Kimya Bölümü
dc.contributor.saüauthor	Yıldırım, Kudret
dc.contributor.saüauthor	Kuru, Ali
dc.relation.journal	JOURNAL OF CHEMICAL RESEARCH
dc.identifier.wos	WOS:000325390100013
dc.identifier.doi	10.3184/174751913X13745069090242
dc.identifier.eissn	2047-6507
dc.contributor.author	Yıldırım, Kudret
dc.contributor.author	Kuru, Ali