Browsing Tıp Fakültesi by Author "Suresh C. Sikka"

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Chronic Escitalopram Treatment Induces Erectile Dysfunction by Decreasing Nitric Oxide Bioavailability Mediated by Increased Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activity and Reactive Oxygen Species Production

Modar Kassan; George F. Lasker; Suresh C. Sikka; Sree Harsha Mandava; Ahmet Gokce; Gökçe, Ahmet; Khalid Matrougui; Wayne J. G. Hellstrom; Philip J. Kadowitz; Ege Can Serefoglu (ELSEVIER SCIENCE INC, 2013)

CONCLUSION The inhibitory effects of escitalopram on erectile and vascular function were not accompanied by a change in endothelial nitric oxide synthase, neuronal nitric oxide synthase, inducible nitric oxide synthase ...
Intratunical Injection of Genetically Modified Adipose Tissue-Derived Stem Cells with Human Interferon alpha-2b for Treatment of Erectile Dysfunction in a Rat Model of Tunica Albugineal Fibrosis

Gökçe, Ahmet; Zakaria Y. Abd Elmageed; George F. Lasker; Mostafa Bouljihad; Stephen E. Braun; Hogyoung Kim; Philip J. Kadowitz; Asim B. Abdel-Mageed; Suresh C. Sikka; Wayne J. Hellstrom (WILEY-BLACKWELL, 2015)

Conclusion. This study documents that transplantation of genetically modified ADSCs, with or without human IFN alpha-2b, attenuated Peyronie's-like changes and enhanced erectile function in a rat model of TAF. Gokce A, Abd ...
Transforming Growth Factor-beta 1 Induced Urethral Fibrosis in a Rat Model

Premsant Sangkum; Gökçe, Ahmet; Ronny B. W. Tan; Mostafa Bouljihad; Hogyoung Kim; Sree Harsha Mandava; Sarmad N. Saleem; George F. Lasker; Faysal A. Yafi; Zakaria Y. Abd Elmageed; Krishnarao Moparty; Suresh C. Sikka; Asim B. Abdel-Mageed; Wayne J. G. Hellstrom (LIPPINCOTT WILLIAMS & WILKINS, 2015)

Conclusions: TGF-beta 1 injection can successfully generate a reproducible rat model of urethral spongiofibrosis. This technique is simple, inexpensive and reproducible. Our series is a proof of concept study. Additional ...
Update on Drug Interactions With Phosphodiesterase-5 Inhibitors Prescribed as First-Line Therapy for Patients with Erectile Dysfunction or Pulmonary Hypertension

Serap Gur; Philip J. Kadowitz; Ahmet Gokce; Gökçe, Ahmet; Suresh C. Sikka; Utku Lokman; Wayne J. G. Hellstrom (BENTHAM SCIENCE PUBL LTD, 2013)

Phosphodiesterase-5 inhibitors (PDE5i, sildenafil, vardenafil, tadalafil and avanafil) are a first-line medical therapy for erectile dysfunction (ED). In all likelihood, PDE5i usage will increase because sildenafil (Viagra(R) ...