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Browsing by Author "Wayne J. G. Hellstrom"

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Androgen Deprivation Therapy Impact on Quality of Life and Cardiovascular Health, Monitoring Therapeutic Replacement

Landon W. Trost; Ege Serefoglu; Ahmet Gokce; Gökçe, Ahmet; Brian J. Linder; Alton O. Sartor; Wayne J. G. Hellstrom (WILEY, 2013)

Introduction Androgen deprivation therapy (ADT) is commonly utilized in the management of both localized and advanced adenocarcinoma of the prostate. The use of ADT is associated with several adverse events, physical ...
Chronic Escitalopram Treatment Induces Erectile Dysfunction by Decreasing Nitric Oxide Bioavailability Mediated by Increased Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activity and Reactive Oxygen Species Production

Modar Kassan; George F. Lasker; Suresh C. Sikka; Sree Harsha Mandava; Ahmet Gokce; Gökçe, Ahmet; Khalid Matrougui; Wayne J. G. Hellstrom; Philip J. Kadowitz; Ege Can Serefoglu (ELSEVIER SCIENCE INC, 2013)

CONCLUSION The inhibitory effects of escitalopram on erectile and vascular function were not accompanied by a change in endothelial nitric oxide synthase, neuronal nitric oxide synthase, inducible nitric oxide synthase ...
Long-Term Revision Rate due to Infection in Hydrophilic-Coated Inflatable Penile Prostheses: 11-Year Follow-up

Ege Can Serefoglu; Sree Harsha Mandava; Ahmet Gokce; Gökçe, Ahmet; Jyoti D. Chouhan; Steve K. Wilson; Wayne J. G. Hellstrom (WILEY-BLACKWELL, 2012)

Introduction. Penile implant surgery continues to be an important option for men with erectile dysfunction. Advancements in technology of implants have contributed to improved survival from mechanical breakdown. Prosthesis ...
Transforming Growth Factor-beta 1 Induced Urethral Fibrosis in a Rat Model

Premsant Sangkum; Gökçe, Ahmet; Ronny B. W. Tan; Mostafa Bouljihad; Hogyoung Kim; Sree Harsha Mandava; Sarmad N. Saleem; George F. Lasker; Faysal A. Yafi; Zakaria Y. Abd Elmageed; Krishnarao Moparty; Suresh C. Sikka; Asim B. Abdel-Mageed; Wayne J. G. Hellstrom (LIPPINCOTT WILLIAMS & WILKINS, 2015)

Conclusions: TGF-beta 1 injection can successfully generate a reproducible rat model of urethral spongiofibrosis. This technique is simple, inexpensive and reproducible. Our series is a proof of concept study. Additional ...
Update on Drug Interactions With Phosphodiesterase-5 Inhibitors Prescribed as First-Line Therapy for Patients with Erectile Dysfunction or Pulmonary Hypertension

Serap Gur; Philip J. Kadowitz; Ahmet Gokce; Gökçe, Ahmet; Suresh C. Sikka; Utku Lokman; Wayne J. G. Hellstrom (BENTHAM SCIENCE PUBL LTD, 2013)

Phosphodiesterase-5 inhibitors (PDE5i, sildenafil, vardenafil, tadalafil and avanafil) are a first-line medical therapy for erectile dysfunction (ED). In all likelihood, PDE5i usage will increase because sildenafil (Viagra(R) ...