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Browsing Makale Koleksiyonu by Author "Yıldırım, Kudret"

Browsing Makale Koleksiyonu by Author "Yıldırım, Kudret"

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  • BAEYER-VILLIGER OXIDATION OF SOME STEROIDS BY Aspergillus tamarii MRC 72400 
    Yıldırım, Kudret (INST ORGANIC CHEM AND BIOCHEM, 2011)
    Biotransformations of epiandrosterone (1), dehydroepiandrosterone (2), testosterone (3), progesterone (4) and pregnenolone (5) by Aspergillus tamarii MRC 72400 for 5 days have been reported and the results of these incubations ...
  • BIOTRANSFORMATION OF (-)-VERBENONE BY Aspergillus tamarii AND Aspergillus terreus 
    Yıldırım, Kudret; Yılmazer Keskin, Semra (INST ORGANIC CHEM AND BIOCHEM, 2010)
    The biotransformations of (-)-verbenone by Aspergillus tamarii and Aspergillus terreus were described. The biotransformation of (-)-verbenone with A. tamarii and A. terreus for 7 days gave (-)-10-hydroxyverbenone. The ...
  • Biotransformation of (-)-verbenone by some fungi 
    Yıldırım, Kudret (SCIENCE REVIEWS 2000 LTD, 2011)
    Biotransformation of (-)-verbenone by Aspergillus niger NRRL 330, Aspergillus wentii MRC 200316 and Penicillium digitatum MRC 500787 afforded (-)-10-hydroxyverbenone. Incubation with A. niger NRRL 330 resulted in with the ...
  • Biotransformation of 19-nortestosterone by Aspergillus wentii MRC 200316 
    Yıldırım, Kudret (SAGE PUBLICATIONS LTD, 2012)
    Incubation of 19-nortestosterone 1 with Aspergillus wentii MRC 200316 for 5 days afforded 10 beta-hydroxy-19-nortestosterone 2 (2%), 6 beta-hydroxy-19-nortestosterone 3 (60%), and 14 alpha-hydroxy-19-nortestosterone 4 (5%).
  • Biotransformation of androst-4-ene-3,17-dione by some fungi 
    Yıldırım, Kudret; Kuru, Ali; Ece Keskin; Aylin Salihoglu; Neslihan Bukum (SAGE PUBLICATIONS LTD, 2017)
    The incubations of androst-4-ene-3,17-dione with Aspergillus candidus MRC 200634, Aspergillus tamarii MRC 72400, Aspergillus wentii MRC 200316 and Mucor hiemalis MRC 70325 for 5 days are reported. A. candidus MRC 200634 ...
  • Biotransformation of some steroids by Aspergillus candidus 
    Yıldırım, Kudret; Kuru, Ali (SAGE PUBLICATIONS LTD, 2015)
    The biotransformation of dehydroepiandrosterone, progesterone and pregnenolone by Aspergillus candidus MRC 200634 for 5 days is reported. Dehydroepiandrosterone was hydroxylated at C-6 beta, C-7 beta, C-7 alpha, C-11 alpha ...
  • BIOTRANSFORMATION OF SOME STEROIDS BY Aspergillus terreus MRC 200365 
    Yıldırım, Kudret (INST ORGANIC CHEM AND BIOCHEM, 2010)
    The biotransformations of testosterone, epiandrosterone, progesterone and pregnenolone by Aspergillus terreus MRC 200365 for five days were described. The biotransformation of testosterone afforded testolactone. The ...
  • Biotransformation of Some Steroids by Aspergillus wentii 
    Yıldırım, Kudret (WALTER DE GRUYTER GMBH, 2010)
    First steroid biotransformations performed by Aspergillus wentii MRC 200316 are reported. Testosterone (1) yields 6 beta-hydroxytestosterone (3) and 14 alpha-hydroxytestosterone (4) while progesterone (2) yields 11 ...
  • Biotransformation of some steroids by Mucor hiemalis MRC 70325 
    Yıldırım, Kudret; Kuru, Ali (SAGE PUBLICATIONS LTD, 2013)
    In this work, incubations of testosterone, dehydroepiandrosterone and pregnenolone with Mucor hiemalis MRC 70325 have been reported. Incubation of testosterone afforded androst-4-en-3,17-dione (3%), 14 alpha-hydroxyandrost-4- ...
  • BIOTRANSFORMATION OF TESTOSTERONE AND PROGESTERONE BY Penicillium digitatum MRC 500787 
    Yıldırım, Kudret (INST ORGANIC CHEM AND BIOCHEM, 2010)
    The biotransformation of testosterone and progesterone by Penicillium digitatum MRC 500787 for 5 days is described. The biotransformation of testosterone afforded 5 alpha-androstane-3,17-dione, 3 alpha-hydroxy-5 ...
  • Biotransformation of testosterone by Cladosporium sphaerospermum 
    Yıldırım, Kudret; Kuru, Ali; Sengul Yilmaz (TAYLOR & FRANCIS LTD, 2019)
    Incubation of testosterone 1 with Cladosporium sphaerospermum MRC 70266 afforded six metabolites and two of these metabolites, 6?,16?,17?-trihydroxyandrost-4-en-3-one 6 and 6?,12?,17?-trihydroxyandrost-4-en-3-one 7, were ...
  • Biotransforrnation of testosterone by Ulocladium chartarum MRC 72584 
    Yıldırım, Kudret; Kuru, Ali; Sengul Yilmaz (SCIENCE REVIEWS 2000 LTD, 2018)
    The incubation of testosterone 1 with Ulocladium chartarum MRC 72584 has been reported. U. chartarum MRC 72584 hydroxylated testosterone 1 at C-7 beta, C-6 beta, C-14 alpha and C-12 beta, accompanied by a 5 alpha-reduction ...
  • Hydrolysis of steroidal esters catalysed by tetracyanoethylene 
    Yıldırım, Kudret (1998)
    Tetracyanoethylene has been shown to be a mild catalyst which possesses some stereoselectivity, for the hydrolysis of the esters of steroidal alcohols.
  • Microbial hydroxylation of epiandrosterone by Aspergillus candidus 
    Yıldırım, Kudret; Kuru, Ali (TAYLOR & FRANCIS LTD, 2017)
    In this work, Aspergillus candidus MRC 22634 converted epiandosterone 1 into 10 hydroxylated metabolites. A. candidus has been shown to hydroxylate 1 predominantly at C-11, C-1, and C-15 with minor hydroxylations occurring ...
  • MICROBIAL HYDROXYLATION OF SOME STEROIDS BY Aspergillus wentii MRC 200316 
    Yıldırım, Kudret (INST ORGANIC CHEM AND BIOCHEM, 2010)
    Biotransformations of epiandrosterone (1), dehydroepiandrosterone (2) and pregnenolone (3) by Aspergillus wentii MRC 200316 for 5 days have been reported. Incubation of epiandrosterone (1) afforded 11 alpha-hydroxy-5 ...
  • Microbial transformation of androstenedione by Cladosporium sphaerospermum and Ulocladium chartarum 
    Yıldırım, Kudret; Kuru, Ali; Eda Kucukbasol (TAYLOR & FRANCIS LTD, 2019)
    In this work, incubations of androstenedione 1 with Cladosporium sphaerospermum MRC 70266 and Ulocladium chartarum MRC 72584 have been reported. C. sphaerospermum MRC 70266 mainly hydroxylated 1 at C-6 beta, accompanied ...
  • Microbial transformation of epiandrosterone by Aspergillus sydowii 
    Yıldırım, Kudret; Kuru, Ali (SAGE PUBLICATIONS LTD, 2016)
    Incubation of epiandrosterone with Aspergillus sydowii MRC 200653 afforded ten metabolites. The fungal dehydrogenation of epiandrosterone is reported for the first time. The formation of the major metabolite, 6 ...
  • Microbial transformation of some steroids by Cladosporium cladosporioides MRC 70282 
    Yıldırım, Kudret; Kuru, Ali; Rasit Fikret Yilmaz (SCIENCE REVIEWS 2000 LTD, 2018)
    Incubation of testosterone, androstenedione and progesterone with Cladosporium cladosporioides MRC 70282 for 5 days is reported. Testosterone was hydroxylated at C-16 beta and then oxidised at C-16. This was accompanied ...
  • Preparation of androstanes related to aphidicolin 
    Yıldırım, Kudret (INST ORGANIC CHEM AND BIOCHEM, 2007)
    The preparation of 3 alpha, 4 alpha, 17 beta-trihydroxy-, 3 alpha, 4 alpha, 16 alpha, 17 alpha- and 2 alpha, 3 alpha, 16 alpha, 17 alpha-tetrahydroxy-5 alpha- androstane derivatives (5, 11, 18) from testosterone as steroidal ...
  • Steroidal Aphidicolin Anologues Derived from Pregnenolone 
    Yıldırım, Kudret (1999)