The Determination of Timolol Maleate Using Silver/Tannic Acid/Titanium Oxide Nanocomposite as an Electrochemical Sensor in Real Samples

Mehmandoust, Mohammad; Cakar, Soner; Ozacar, Mahmut; Erk, Nevin

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dc.contributor.authors	Mehmandoust, Mohammad; Cakar, Soner; Ozacar, Mahmut; Erk, Nevin
dc.date.accessioned	2022-12-20T13:25:05Z
dc.date.available	2022-12-20T13:25:05Z
dc.date.issued	2022
dc.identifier.issn	1040-0397
dc.identifier.uri	http://dx.doi.org/10.1002/elan.202100363
dc.identifier.uri	https://hdl.handle.net/20.500.12619/99190
dc.description	Bu yayının lisans anlaşması koşulları tam metin açık erişimine izin vermemektedir.
dc.description.abstract	Herein, a portable and cost-effective electrochemical sbased on Silver/tannic acid/titanium dioxide/glassy carbon electrode (Ag/TA@ TiO2/GCE) was fabricated to determine timolol(TM) assay. The Ag/TA@TiO2/GCE offered an irreversible oxidation peak at +0.99 V, and exhibited an extraordinary electrochemical performance with a wide linear working ranges from 0.01-0.84 and 0.84-49.0 mu M and a low detection limit of 5.2 nM. The detection of TM in the presence of interfering agents and real samples was also analyzed. The sensor's selectivity was studied by comparing the binding of TM, propranolol, nebivolol, and metoprolol. The developed electrochemical sensing platform could have promising potential for the determination of TM in clinical samples.
dc.language	English
dc.language.iso	eng
dc.relation.isversionof	10.1002/elan.202100363
dc.subject	Chemistry
dc.subject	Electrochemistry
dc.subject	Beta-blocker medication
dc.subject	Timolol maleate
dc.subject	Electrochemical sensor
dc.subject	Chronoamperometry
dc.subject	real samples
dc.title	The Determination of Timolol Maleate Using Silver/Tannic Acid/Titanium Oxide Nanocomposite as an Electrochemical Sensor in Real Samples
dc.contributor.authorID	Mehmandoust, Mohammad/0000-0002-8545-0603
dc.identifier.volume	34
dc.identifier.startpage	1150
dc.identifier.endpage	1162
dc.relation.journal	ELECTROANALYSIS
dc.identifier.issue	7
dc.identifier.doi	10.1002/elan.202100363
dc.identifier.eissn	1521-4109
dc.contributor.author	Mehmandoust, Mohammad
dc.contributor.author	Cakar, Soner
dc.contributor.author	Ozacar, Mahmut
dc.contributor.author	Erk, Nevin
dc.relation.publicationcategory	Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı