dc.date.accessioned |
2021-06-08T09:11:47Z |
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dc.date.available |
2021-06-08T09:11:47Z |
|
dc.date.issued |
2020 |
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dc.identifier.issn |
1386-1425 |
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dc.identifier.uri |
https://hdl.handle.net/20.500.12619/96088 |
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dc.description |
The authors are indebted to the TUBITAK (Scientific and Technological Research Council of Turkey with grant number 217Z043) and the KMU Scientific Research Project Center for their support with the project 30-M-16 to provide the Gaussian 09W and Gauss view 5.0.8 programs. Also, authors thank Abdurrahman KARAGOZ for help with DFT studies. |
|
dc.description |
Bu yayının lisans anlaşması koşulları tam metin açık erişimine izin vermemektedir. |
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dc.description.abstract |
Utilization of fluorescent techniques in detection of various metal ions actively pursued allow ultrasensitive and selective detections of metal ions and prevent the adverse effect of cations such as aluminum (III) ions. In this study, two novel fluorescent chemosensors containing thiazole derivatives, ((E)-2-(4-hydroxy-3-(((2-hydroxyphenyl)imino)methyl)phenyl)-3-phenyl thiazolidin-4-one) AM1 and (2,3-bis(4-hydroxy-3-((E)-((2hydroxyphenyl)imino) methyl) phenyl) thiazolidin-4-one) AM2, have been fabricated. The probes AM1 and AM2 were prepared using the condensation reaction between 2-hydroxy-5-(4-oxo-3-phenyl thiazolidin-2-yl) benzaldehyde and 2-aminophenol for the probe AM1 and 5,5'-(4-oxothiazolidine-2,3-diyl)bis(2-hydroxy benzaldehyde) and 2-aminophenol for the probe AM2. Afterwards, they were analyzed by various types of NMR and FT-IR spectroscopy, ESI-MS spectra, and elemental anayzer. As a second step, each fabricated chemosensor was able to use turn on fluorescence sensing for detecting of Al3+ ions in ACN/H2O (v/v = 50/50, 10.0 mu M, pH = 7.0) solution. Clear complexes formed between the probe AM1 and Al3+ ions and also the probe AM2 and Al-3 (+) ions was determined by not only H-1 NMR titration study but also calculated by using the Job's plot. The limit of detection (LOD) value was found to be 0.11 mu M(AM1) and 4.4 mu M(AM2) for Al3+ ions. Likewise, cell imaging and in vitro cytotoxicity experiments of Al3+ ions in Human epithelium Lovo cells exhibited that prepared chemosensors had low cytotoxicity and blue fluorescence when they treated with of Al3+ ions in the cellular system. (C) 2020 Elsevier B.V. All rights reserved. |
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dc.description.sponsorship |
TUBITAK (Scientific and Technological Research Council of Turkey)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [217Z043, 30-M-16]; KMU Scientific Research Project Center [30-M-16] |
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dc.language |
English |
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dc.language.iso |
eng |
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dc.publisher |
PERGAMON-ELSEVIER SCIENCE LTD |
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dc.relation.isversionof |
10.1016/j.saa.2020.118431 |
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dc.rights |
info:eu-repo/semantics/closedAccess |
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dc.subject |
AL3+ ION |
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dc.subject |
PROBE |
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dc.subject |
RHODAMINE |
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dc.subject |
SENSOR |
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dc.subject |
DERIVATIVES |
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dc.subject |
HG2+ |
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dc.title |
Thiazolidine based fluorescent chemosensors for aluminum ions and their applications in biological imaging |
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dc.type |
Article |
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dc.identifier.volume |
238 |
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dc.relation.journal |
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY |
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dc.identifier.doi |
10.1016/j.saa.2020.118431 |
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dc.identifier.eissn |
1879-2731 |
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dc.contributor.author |
Aydin, Duygu |
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dc.contributor.author |
Karakilic, Emel |
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dc.contributor.author |
Karakurt, Serdar |
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dc.contributor.author |
Baran, Arif |
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dc.relation.publicationcategory |
Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı |
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dc.identifier.pmıd |
32413718 |
|