dc.date.accessioned |
2021-06-03T11:02:21Z |
|
dc.date.available |
2021-06-03T11:02:21Z |
|
dc.date.issued |
2021 |
|
dc.identifier.issn |
2148-2373 |
|
dc.identifier.uri |
https://www.doi.org/10.14235/bas.galenos.2020.4884 |
|
dc.identifier.uri |
https://hdl.handle.net/20.500.12619/95463 |
|
dc.description |
This work was supported by Gilead Sciences. |
|
dc.description |
Bu yayın 06.11.1981 tarihli ve 17506 sayılı Resmî Gazete’de yayımlanan 2547 sayılı Yükseköğretim Kanunu’nun 4/c, 12/c, 42/c ve 42/d maddelerine dayalı 12/12/2019 tarih, 543 sayılı ve 05 numaralı Üniversite Senato Kararı ile hazırlanan Sakarya Üniversitesi Açık Bilim ve Açık Akademik Arşiv Yönergesi gereğince açık akademik arşiv sistemine açık erişim olarak yüklenmiştir. |
|
dc.description |
Bu yayın 06.11.1981 tarihli ve 17506 sayılı Resmî Gazete’de yayımlanan 2547 sayılı Yükseköğretim Kanunu’nun 4/c, 12/c, 42/c ve 42/d maddelerine dayalı 12/12/2019 tarih, 543 sayılı ve 05 numaralı Üniversite Senato Kararı ile hazırlanan Sakarya Üniversitesi Açık Bilim ve Açık Akademik Arşiv Yönergesi gereğince açık akademik arşiv sistemine açık erişim olarak yüklenmiştir. |
|
dc.description.abstract |
Objective: The purpose of this study is to examine the levels of C-reactive protein (CRP) and D-dimer by age and gender in the pandemic caused by the new coronavirus. Methods: Coronavirus disease-19 (COVID-19) diagnoses were made according to the results of real-time polymerase chain reaction and lung computed tomography (n=70). In the study, CRP and coagulation were examined as indicators of inflammation, and D-dimer was examined as an indicator of fibrinolytic system activity. Patients' age, gender, and CRP and D-dimer values were analyzed with Spearman's rho correlation, whereas the gender factor was analyzed with the Mann-Whitney U test. Results: Although D-dimer levels were high in women, there was no statistical significance. A correlation was identified between CRP and gender, and the levels in male patients were higher (p=0.049). A positive correlation was found between the patients' age and CRP and D-dimer findings. Conclusion: There are two main findings in this study. First, age and gender arc essential parameters in disease findings due to the COVID-19 pandemic. Their importance overlaps with the finding that inflammation is severe in elderly males and that the mortality is higher than in younger individuals. Second, the CRP and D-dimer test results can he used as practical and reliable biomarkers for COVID-19. We propose that if these two tests, which arc already used routinely, arc interpreted with consideration of age and gender, they can he used more efficiently in early diagnosis and isolation. |
|
dc.description.sponsorship |
Gilead SciencesGilead Sciences |
|
dc.language |
English |
|
dc.language.iso |
eng |
|
dc.publisher |
BEZMIALEM VAKIF UNIV |
|
dc.relation.isversionof |
10.14235/bas.galenos.2020.4884 |
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dc.rights |
info:eu-repo/semantics/openAccess |
|
dc.subject |
SARS-Cov-2 |
|
dc.subject |
COVID-19 |
|
dc.subject |
C-reactive protein |
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dc.subject |
D-dimer |
|
dc.title |
Investigation of C-reactive Protein and D-dimer Findings in Patients with COVID-19 |
|
dc.type |
Article |
|
dc.identifier.volume |
9 |
|
dc.identifier.startpage |
4 |
|
dc.identifier.endpage |
8 |
|
dc.relation.journal |
BEZMIALEM SCIENCE |
|
dc.identifier.wos |
WOS:000616392300006 |
|
dc.identifier.doi |
10.14235/bas.galenos.2020.4884 |
|
dc.contributor.author |
Yazar, Hayrullah |
|
dc.contributor.author |
Kayacan, Yildirim |
|
dc.contributor.author |
Ozdin, Mehmet |
|
dc.relation.publicationcategory |
Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı |
|
dc.rights.openaccessdesignations |
DOAJ Gold |
|