dc.rights.license |
DOAJ Gold |
|
dc.date.accessioned |
2021-06-03T08:20:18Z |
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dc.date.available |
2021-06-03T08:20:18Z |
|
dc.date.issued |
2020 |
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dc.identifier.uri |
www.doi.org/10.1590/1806-9282.66.S2.65 |
|
dc.identifier.uri |
https://hdl.handle.net/20.500.12619/95129 |
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dc.description |
Bu yayın 06.11.1981 tarihli ve 17506 sayılı Resmî Gazete’de yayımlanan 2547 sayılı Yükseköğretim Kanunu’nun 4/c, 12/c, 42/c ve 42/d maddelerine dayalı 12/12/2019 tarih, 543 sayılı ve 05 numaralı Üniversite Senato Kararı ile hazırlanan Sakarya Üniversitesi Açık Bilim ve Açık Akademik Arşiv Yönergesi gereğince açık akademik arşiv sistemine açık erişim olarak yüklenmiştir. |
|
dc.description.abstract |
INTRODUCTION: This study aims to evaluate changes in hematological parameters after the follow-up of patients who received treatment with favipiravir due to COVID-19 infections. METHODS: Sixty-two cases receiving favipiravir treatment for at least five days due to COVID-19 infection were evaluated retrospectively. Parameters including age, gender, nasopharyngeal swab positivity, and chronic diseases were analyzed. Hematologic parameters were analyzed before and after the treatment. RESULTS: The mean age of the patients receiving treatment with favipiravir was 63.7 +/- 12.3 years. Nasopharyngeal swab positivity was detected in 67.7%. The most common comorbid conditions detected in patients were hypertension in 25 cases (40.3%) and diabetes in 16 cases (25.8%). In the statistical analysis of the hematological parameters before and after treatment with favipiravir, WBC, PT-PTT-INR levels were found to be unaffected; the mean RBC was found to have decreased from 4.33 +/- 0.58 M/uL to 4.16 +/- 0.54 M/uL (p:0.003); the median hemoglobin level was found to have decreased from 12.3 g/dl to 11.9 g/dl (p:0.041); the hematocrit level decreased from 38.1% +/- 4.8 to 36.9% +/- 4.2 (p:0.026); the median neutrophil count decreased from 4.57 K/uL to 3.85 K/uL (p:0.001); the mean lymphocyte count increased from 1.22 +/- 0.53 K/uL to 1.84 +/- 1.79 K/uL (p:0.000); and the mean platelet count increased from 244.1 +/- 85.1 K/uL to 281.9 +/- 103.3 K/uL (p:0.005). CONCLUSION: We concluded that the pathological effect of treatment with favipiravir on the hematologic system was the suppression in the erythrocyte series, and there were no adverse effects in other hematologic parameters. |
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dc.language |
English |
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dc.language.iso |
İngilizce |
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dc.publisher |
ASSOC MEDICA BRASILEIRA |
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dc.relation.isversionof |
10.1590/1806-9282.66.S2.65 |
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dc.rights |
info:eu-repo/semantics/openAccess |
|
dc.subject |
T-705 FAVIPIRAVIR |
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dc.subject |
VIRUS |
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dc.subject |
Coronavirus Infections |
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dc.subject |
Antiviral Agents |
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dc.subject |
Blood |
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dc.subject |
Blood Cells |
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dc.subject |
Favipiravir |
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dc.title |
The effects of favipiravir on hematological parameters of covid-19 patients |
|
dc.type |
Article |
|
dc.contributor.authorID |
Aydin, Abdulkadir/0000-0003-0663-586X |
|
dc.contributor.authorID |
kocayigit, havva/0000-0002-8719-7031 |
|
dc.contributor.authorID |
Reis, AlessanRSS/0000-0001-8486-7469 |
|
dc.contributor.authorID |
dheir, hamad/0000-0002-3569-6269 |
|
dc.contributor.authorID |
YAYLACI, SELCUK/0000-0002-6768-7973 |
|
dc.contributor.authorID |
Varim, Ceyhun/0000-0002-8369-0857 |
|
dc.contributor.authorID |
KARABAY, OGUZ/0000-0003-1514-1685 |
|
dc.identifier.volume |
66 |
|
dc.identifier.startpage |
65 |
|
dc.identifier.endpage |
70 |
|
dc.relation.journal |
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA |
|
dc.identifier.wos |
WOS:000574277200017 |
|
dc.identifier.doi |
10.1590/1806-9282.66.S2.65 |
|
dc.identifier.eissn |
1806-9282 |
|
dc.contributor.author |
Yaylaci, Selcuk |
|
dc.contributor.author |
Dheir, Hamad |
|
dc.contributor.author |
Senocak, Didar |
|
dc.contributor.author |
Genc, Ahmed Bilal |
|
dc.contributor.author |
Kocayigit, Havva |
|
dc.contributor.author |
Cekic, Deniz |
|
dc.contributor.author |
Varim, Ceyhun |
|
dc.contributor.author |
Aydin, Abdulkadir |
|
dc.contributor.author |
Koroglu, Mehmet |
|
dc.contributor.author |
Karabay, Oguz |
|
dc.relation.publicationcategory |
Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı |
|
dc.identifier.pmıd |
32965359 |
|