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The effects of zoledronic acid treatment on depression and quality of life in women with postmenopausal osteoporosis: A clinical trial study

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dc.contributor.authors Gokosmanoglu, F; Varim, C; Atmaca, A; Atmaca, MH; Colak, R;
dc.date.accessioned 2020-02-27T08:53:06Z
dc.date.available 2020-02-27T08:53:06Z
dc.date.issued 2016
dc.identifier.citation Gokosmanoglu, F; Varim, C; Atmaca, A; Atmaca, MH; Colak, R; (2016). The effects of zoledronic acid treatment on depression and quality of life in women with postmenopausal osteoporosis: A clinical trial study. Journal of Research in Medical Sciences, 21, -
dc.identifier.issn 1735-1995
dc.identifier.uri https://doi.org/10.4103/1735-1995.193503
dc.identifier.uri https://hdl.handle.net/20.500.12619/67061
dc.description.abstract Background: Osteoporosis affects quality of life (QoL) and may lead to depression in women. he purpose of this study was to evaluate the effects of zoledronic acid (ZA) treatment on depression and QoL in women with postmenopausal osteoporosis (PO). Materials and Methods: A total of 88 newly diagnosed women with PO were included in this study. All patients were treated with once-yearly ZA (5 mg). A QoL questionnaire from the European Foundation for Osteoporosis and Beck Depression Inventory were given to patients at baseline and at 12 months. he results for baseline and post - 12th month were compared, and bone mineral density (BMD) levels were compared. Results: he consumption of once-yearly ZA (5 mg) treatment increases BMD at levels of lumbers 1-4 (P = 0.026), total Hip T score's P value is same as femoral neck (P: 0,033). ZA 5 mg treatment also improved QoL (P = 0.001) and reduced depression (P = 0.001). Conclusion: ZA treatment increases BMD levels and QoL while reducing depression. Once-yearly ZA (5 mg) may be considered for postmenopausal women as a first-line treatment.
dc.language English
dc.publisher MEDKNOW PUBLICATIONS & MEDIA PVT
dc.title The effects of zoledronic acid treatment on depression and quality of life in women with postmenopausal osteoporosis: A clinical trial study
dc.type Article
dc.identifier.volume 21
dc.contributor.department Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü
dc.contributor.saüauthor Varım, Ceyhun
dc.relation.journal Journal of Research in Medical Sciences
dc.identifier.wos WOS:000394506300013
dc.identifier.doi 10.4103/1735-1995.193503
dc.identifier.eissn 1735-7136
dc.contributor.author Feyzi Gokosmanoglu
dc.contributor.author Varım, Ceyhun
dc.contributor.author Aysegul Atmaca
dc.contributor.author Mehmet Hulusi Atmaca
dc.contributor.author Ramis Colak


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