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The antibacterial effects of bilirubin on gram-negative bacterial agents of sepsis.

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dc.contributor.authors Terzi, HA; Kardes, H; Atasoy, AR; Aykan, SB; Karakece, E; Ustundag, GH; Ermis, B; Ciftci, IH;
dc.date.accessioned 2020-02-27T08:47:57Z
dc.date.available 2020-02-27T08:47:57Z
dc.date.issued 2016
dc.identifier.citation Terzi, HA; Kardes, H; Atasoy, AR; Aykan, SB; Karakece, E; Ustundag, GH; Ermis, B; Ciftci, IH; (2016). The antibacterial effects of bilirubin on gram-negative bacterial agents of sepsis.. BIOMEDICAL RESEARCH-INDIA, 27, 209-207
dc.identifier.issn 0970-938X
dc.identifier.uri https://hdl.handle.net/20.500.12619/66924
dc.description.abstract In this study, we investigated the antibacterial effects of bilirubin on certain Gram-negative bacteria using both agar dilution and liquid microdilution methods. Twenty-five strains each of Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa strains, isolated from various clinical samples in the medical microbiology laboratory of our hospital, were evaluated. Stock solutions of bilirubin (5 mg, 10 mg, and 15 mg/dl) (AppliChem, GmbH, Darmstadt, Germany) were prepared for agar dilution method. Aliquots of bilirubin stock solutions were added to liquid brain heart infusion medium in sterile microplates for liquid dilution methods. The average bilirubin MICs were 61.44, 62.72, >= 64.00, and >= 64.00 mu g/mL for E. coli, K. pneumoniae, A. baumannii, and P. aeruginosa. In agar and liquid dilution methods, all tested bacteria grew at all bilirubin concentrations used. Bilirubin had no in vitro antibacterial effect on E. coli, K. pneumoniae, A. baumannii, or P. aeruginosa.
dc.language English
dc.publisher ALLIED ACAD
dc.subject Research & Experimental Medicine
dc.title The antibacterial effects of bilirubin on gram-negative bacterial agents of sepsis.
dc.type Article
dc.identifier.volume 27
dc.identifier.startpage 207
dc.identifier.endpage 209
dc.contributor.department Sakarya Üniversitesi/Tıp Fakültesi/Temel Tıp Bilimleri Bölümü
dc.contributor.saüauthor Terzi, Hüseyin Agah
dc.contributor.saüauthor Atasoy, Ali Rıza
dc.contributor.saüauthor Aykan, Şadiye Berna
dc.contributor.saüauthor Ermiş, Bahri
dc.contributor.saüauthor Çiftci, İhsan Hakkı
dc.relation.journal BIOMEDICAL RESEARCH-INDIA
dc.identifier.wos WOS:000374112200035
dc.identifier.eissn 0976-1683
dc.contributor.author Terzi, Hüseyin Agah
dc.contributor.author Hakan Kardes
dc.contributor.author Atasoy, Ali Rıza
dc.contributor.author Aykan, Şadiye Berna
dc.contributor.author Engin Karakece
dc.contributor.author Gonca Handan Ustundag
dc.contributor.author Ermiş, Bahri
dc.contributor.author Çiftci, İhsan Hakkı


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