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The Seroprevalence of Hand-Foot-Mouth Disease in Preschool Children

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dc.contributor.authors Cinar, EM; Kosecik, M; Aslan, FG; Buyukavci, M; Koroglu, M; Elmas, B; Altindis, M;
dc.date.accessioned 2020-02-27T08:28:50Z
dc.date.available 2020-02-27T08:28:50Z
dc.date.issued 2019
dc.identifier.citation Cinar, EM; Kosecik, M; Aslan, FG; Buyukavci, M; Koroglu, M; Elmas, B; Altindis, M; (2019). The Seroprevalence of Hand-Foot-Mouth Disease in Preschool Children. JOURNAL OF PEDIATRIC INFECTIOUS DISEASES, 14, 175-171
dc.identifier.issn 1305-7707
dc.identifier.uri https://doi.org/10.1055/s-0039-1685162
dc.identifier.uri https://hdl.handle.net/20.500.12619/66095
dc.description.abstract Hand-foot-mouth disease (HFMD) is a systemic and mostly uncomplicated infectious disease caused by the virus of the enterovirus family and manifests as skin and mucosal lesions. Enterovirus 71 (EV71) and coxsackievirus A16 (CA16) are the most commonly detected infectious agents. It is generally observed in children under 5 years of age. In this study, our objective was to determine the seroprevalence of HFMD in preschool children in Sakarya region. A total of 380 children between 1 and 6 years of age were included in the study. Sociodemographic information, clinical findings, and possible risk factors were recorded on a data collection form. Later, serum anti-EV71 and anti-CA16 IgG (immunoglobulin G) antibodies were measured by ELISA. Amongst the 380 children, EV71 IgG positivity was 57.9% and CA16 IgG antibody positivity was 57.4%. There was no difference in seroprevalence between the genders (p > 0.05). Anti-EV71 and anti-CA16 IgG antibody positivity was significantly higher in children aged 1, 2, 3, and 4 years than in 5-year olds (p < 0.05). Seroprevalence was significantly lower in children of mothers who washed their hands before feeding (p < 0.01). High HFMD seroprevalence (> 50%) was observed in the preschool period in the Sakarya region, especially in children aged 1 to 4 years. To prevent infections for which there is no specific treatment, it is very important that the hygiene rules are complied with; in particular, children and their caregivers should pay attention to hand cleansing. We believe that more seroprevalence studies should be performed from different regions to show the status of the disease in our country.
dc.language English
dc.publisher GEORG THIEME VERLAG KG
dc.subject Pediatrics
dc.title The Seroprevalence of Hand-Foot-Mouth Disease in Preschool Children
dc.type Article
dc.identifier.volume 14
dc.identifier.startpage 171
dc.identifier.endpage 175
dc.contributor.department Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü
dc.contributor.saüauthor Çınar, Esma Merve
dc.contributor.saüauthor Kösecik, Mustafa
dc.contributor.saüauthor Aslan, Ferhat Gürkan
dc.contributor.saüauthor Büyükavcı, Mustafa
dc.contributor.saüauthor Köroğlu, Mehmet
dc.contributor.saüauthor Elmas, Bahri
dc.contributor.saüauthor Altındiş, Mustafa
dc.relation.journal JOURNAL OF PEDIATRIC INFECTIOUS DISEASES
dc.identifier.wos WOS:000477660300005
dc.identifier.doi 10.1055/s-0039-1685162
dc.identifier.eissn 1305-7693
dc.contributor.author Çınar, Esma Merve
dc.contributor.author Kösecik, Mustafa
dc.contributor.author Aslan, Ferhat Gürkan
dc.contributor.author Büyükavcı, Mustafa
dc.contributor.author Köroğlu, Mehmet
dc.contributor.author Elmas, Bahri
dc.contributor.author Altındiş, Mustafa


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