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Browsing Makale Koleksiyonu by Author "Güney Eskiler, Gamze"

Browsing Makale Koleksiyonu by Author "Güney Eskiler, Gamze"

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  • IL-6 mediated JAK/STAT3 signaling pathway in cancer patients with cachexia 
    Guney G. Eskiler; Güney Eskiler, Gamze; E. Bezdegumeli; Z. Ozman; Deveci A. Ozkan; Deveci Özkan, Asuman; Bilir, Cemil; Bilir, Cemil; B. N. Kucukakca; M. N. Ince; A. Y. Men; O. Aktas; Y. E. Horoz; D. Akpinar (COMENIUS UNIV, 2019)
    CONCLUSION: STAT3 may be considered as a therapeutic target for cachectic patients with gastric, lung and breast cancer. Furthermore, IL-6 mediates STAT3 activation in cachectic gastric and breast cancer patients (Tab. 5, ...
  • Inhibition of TLR4/TRIF/IRF3 Signaling Pathway by Curcumin in Breast Cancer Cells 
    Güney Eskiler, Gamze; Deveci Özkan, Asuman; Kaleli, Süleyman; Bilir, Cemil (CANADIAN SOC PHARMACEUTICAL SCIENCES, 2019)
    Purpose: Toll-like receptor 4 (TLR4) is over-expressed in breast tumors and thus contributing to the tumor progression and metastasis. Natural products have drawn attention in cancer immunotherapy due to their various ...
  • Synergistic Effects of Nobiletin and Sorafenib Combination on Metastatic Prostate Cancer Cells 
    Güney Eskiler, Gamze; Deveci Özkan, Asuman; Bilir, Cemil; Kaleli, Süleyman (ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 2019)
    Objective: Herein we, for the first time, investigated a potential synergistic effect of nobiletin (NOB) and sorafenib (SOR) on PC-3 prostate cancer and HUVEC control cell lines.Methods: In order to determine the cytotoxic ...