Browsing Araştırma Çıktıları / Research Outputs by Subject "Poly (ADP -ribose) polymerase (PARP)"

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Therapeutic potential of the PI3K inhibitor LY294002 and PARP inhibitor Talazoparib combination in BRCA-deficient triple negative breast cancer cells

Eskiler, Gamze Guney; Ozturk, Melek (2022)

Poly (ADP-ribose) polymerase (PARP) inhibitors provide a promising therapeutic strategy for triple-negative breast cancers (TNBCs) with BRCA1/2 mutation. However, acquire resistance mechanisms and genetic alterations limit ...