Biotransformation of testosterone by Cladosporium sphaerospermum

Yıldırım, Kudret; Kuru, Ali; Sengul Yilmaz

dc.contributor.authors	Yildirim, K; Kuru, A; Yilmaz, S;
dc.date.accessioned	2020-02-24T14:22:07Z
dc.date.available	2020-02-24T14:22:07Z
dc.date.issued	2019
dc.identifier.citation	Yildirim, K; Kuru, A; Yilmaz, S; (2019). Biotransformation of testosterone by Cladosporium sphaerospermum. BIOCATALYSIS AND BIOTRANSFORMATION, 37, 413-409
dc.identifier.issn	1024-2422
dc.identifier.uri	https://doi.org/10.1080/10242422.2019.1583747
dc.identifier.uri	https://hdl.handle.net/20.500.12619/45315
dc.description.abstract	Incubation of testosterone 1 with Cladosporium sphaerospermum MRC 70266 afforded six metabolites and two of these metabolites, 6?,16?,17?-trihydroxyandrost-4-en-3-one 6 and 6?,12?,17?-trihydroxyandrost-4-en-3-one 7, were determined as new compounds. The fungus mainly hydroxylated testosterone 1 at C-6?, accompanied by some minor hydroxylations at C-7?, C-12?, C-15? and C-16?. A minor oxidation at C-17 and a minor 5?-reduction were also observed.
dc.language	English
dc.publisher	TAYLOR & FRANCIS LTD
dc.subject	Biotechnology & Applied Microbiology
dc.title	Biotransformation of testosterone by Cladosporium sphaerospermum
dc.type	Article
dc.identifier.volume	37
dc.identifier.startpage	409
dc.identifier.endpage	413
dc.contributor.department	Sakarya Üniversitesi/Fen-Edebiyat Fakültesi/Kimya Bölümü
dc.contributor.saüauthor	Yıldırım, Kudret
dc.contributor.saüauthor	Kuru, Ali
dc.relation.journal	BIOCATALYSIS AND BIOTRANSFORMATION
dc.identifier.wos	WOS:000488469800002
dc.identifier.doi	10.1080/10242422.2019.1583747
dc.identifier.eissn	1029-2446
dc.contributor.author	Yıldırım, Kudret
dc.contributor.author	Kuru, Ali
dc.contributor.author	Sengul Yilmaz