Browsing Tıp Fakültesi by Subject "Chemistry"

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Antimicrobial activities, DNA interactions, spectroscopic (FT-IR and UV-Vis) characterizations, and DFT calculations for pyridine-2-carboxylic acid and its derivates

Tamer, Ömer; Arabacı Tamer, Sevil; Onder Idil; Avcı, Davut; Hatice Vural; Atalay, Yusuf (ELSEVIER SCIENCE BV, 2018)

In this paper, pyridine-2-carboxylic acid, also known as picolinic acid (pic), and its two derivate, 4-methoxy-pyridine-2-carboxylic acid (4-Mpic) and 4-chloro-pyridine-2-carboxylic acid (4-Clpic) have been characterized ...
Asymmetric reduction of acetophenone analogues by Alternaria alternata using ram horn peptone

Kurbanoğlu, Namudar İzzet; Kılıç, Harun (PERGAMON-ELSEVIER SCIENCE LTD, 2007)

Alternaria alternata EBK-4 fungus isolated from a plant sample was evaluated for the asymmetric reduction of acetophenone analogues. In a previous study, this isolate was used for the reduction of acetophenone to 1-phenylethanol ...
Determination of Flurbiprofen in Human Plasma by High-Performance Liquid Chromatography

Bilal Yilmaz; Erdem, Ali Fuat (OXFORD UNIV PRESS INC, 2015)

A simple high-performance liquid chromatography method has been developed for determination of flurbiprofen in human plasma. The method was validated on an Ace C-18 column using UV detection. The mobile phase was ...
Effects of Olanzapine and Clozapine on Radial Maze Performance in Naive and MK-801-Treated Mice

O. Mutlu; I. K. Celikyurt; G. Ulak; Tanyeri, Pelin; Tanyeri, Pelin; F. Y. Akar; F. Erden (GEORG THIEME VERLAG KG, 2012)

Attention, working memory and long-term memory dysfunctions are the most commonly seen cognitive impairments in schizophrenic patients. Conflicting results exist regarding the effects of antipsychotics on cognitive ...
Enantioselective reduction of substituted acetophenones by Aspergillus niger

Kurbanoğlu, Namudar İzzet; Kılıç, Harun (PERGAMON-ELSEVIER SCIENCE LTD, 2007)

Fourteen strains of Aspergillus niger were isolated from soil samples. These isolates were evaluated for tile reduction of acetophenone to 1-phenylethanol. Among the tested isolates, whole cells of the A. niger EBK-9 isolate ...
Novel eugenol bearing oxypropanolamines: Synthesis, characterization, antibacterial, antidiabetic, and anticholinergic potentials

Genç Bilgiçli, Hayriye; Ali Kestane; Parham Taslimi; Karabay, Oğuz; Arlinda Bytyqi-Damoni; Zengin, Mustafa; Ilhami Gulcin (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2019)

Five oxypropanol amine derivatives that four of them are novel have been synthesized with high yields and practical methods. in vitro antibacterial susceptibility of Acinetobacter baumannii, Pseudomonas aeruginosa, Escherichia ...
Novel thymol bearing oxypropanolamine derivatives as potent some metabolic enzyme inhibitors - Their antidiabetic, anticholinergic and antibacterial potentials

Zengin, Mustafa; Genç Bilgiçli, Hayriye; Parham Taslimi; Ali Kestane; Güçlü, Ertuğrul; Öğütlü, Aziz; Karabay, Oğuz; Ilhami Gulcin (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2018)

A series of classical and newly synthesized thymol bearing oxypropanolamine compounds were synthesized and characterized. Their in vitro antibacterial activity on A. baumannii, P. aeruginosa, E. coli and S. aureus strains ...
Production of (R)-1-phenylethanols Through Bioreduction of Acetophenones by a New Fungus Isolate Trichothecium roseum

Taşkın, Mehmet Fatih; Kurbanoğlu, Namudar İzzet; Kılıç, Harun (WILEY, 2010)

A total of 120 fungal strains were isolated from soil samples and evaluated in the bioreduction of substituted acetophenones to the corresponding (R)-alcohols. Among these strains, isolate Trichothecium roseum EBK-18 was ...
Simultaneous Determination of Tramadol and Its Metabolite in Human Urine by the Gas Chromatography-Mass Spectrometry Method

Bilal Yilmaz; Erdem, Ali Fuat (OXFORD UNIV PRESS INC, 2015)

A sensitive and efficient method was developed for determination of tramadol and its metabolite (O-desmethyltramadol) in human urine by gas chromatography-mass spectrometry. Tramadol, O-desmethyltramadol and medazepam ...
Stereospecific synthesis of a DL-gala-aminoquercitol derivative

Kurbanoğlu, Namudar İzzet; Kılıç, Harun; Balci, Mustafa (PERGAMON-ELSEVIER SCIENCE LTD, 2010)

A new aminoquercitol derivative was synthesized starting from 1,4-cyclohexadiene. Photooxygenation of cyclohexa-1,4-diene afforded anti-2,3-dioxabicyclo[2.2.2]oct-7-en-5-yl hydroperoxicle as the main product. The formed ...