DSpace Home
→
Araştırma Çıktıları / Research Outputs
→
WOS İndeksli Yayınlar Koleksiyonu / WOS Indexed Publications Collection
→
Browsing WOS İndeksli Yayınlar Koleksiyonu / WOS Indexed Publications Collection by Author

Browsing WOS İndeksli Yayınlar Koleksiyonu / WOS Indexed Publications Collection by Author "Eskiler, Gamze Guney"

Now showing items 1-17 of 17

Anticancer Properties of Eisenia Foetida Proteins in Prostate Cancer Cells In Vitro

Ozkan, Asuman Deveci; Eskiler, Gamze Guney; Sarihan, Mehmet; Kazan, Nur; Aksoy, Ozlem; Yuksel, Burcu; Betts, Zeynep (2022)

Earthworms are tube-shaped, segmental worms and have a double transport system consisting of earthworm coelomic fluid (ECF) moving within the fluid-filled colon. As one of the naturally available extracts (NAEs), ECF exerts ...
Clinicopathologic features and genetic characteristics of the BRCA1/2 mutation in Turkish breast cancer patients

Cecener, Gulsah; Takanlou, Leila Sabour; Takanlou, Maryam Sabour; Egeli, Unal; Eskiler, Gamze Guney; Aksoy, Secil; Unal, Ufuk; Tezcan, Havva; Eryilmaz, Isil Ezgi; Gokgoz, Mustafa Sehsuvar; Tunca, Berrin; Cubukcu, Erdem; Evrensel, Turkkan; Cetintas, Sibel; Tasdelen, Ismet (ELSEVIER SCIENCE INC, 2020)

The aim of this study was to identify the frequency and spectrum of germline BRCA1/2 pathogenic alterations in a cohort of patients with breast carcinoma. In this study, a total of 603 breast cancer subjects from Turkey ...
Comparison of the anti-cancer activity of 5-aminolevulinic acid-mediated photodynamic therapy after continuous wave and pulse irradiation in different histological types of canine mammary sarcoma tumors

Turna, Ozge; Deveci Ozkan, Asuman; Eskiler, Gamze Guney; Baykal, Aslihan; Ozten, Ozge; Yildirim, Funda; Armutak, Elif Ilkay; Kamanli, Ali Furkan; Lim, Hyun Soo; Kaleli, Suleyman; Kasikci, Guven; Yildiz, Salih Zeki (2023)

Canine mammary sarcoma tumors (CMST) are the most aggressive tumors with poor prognosis in dogs. Due to inadequate treatment options for CMST, recent studies have focused on alternative treatment strategies. We previously ...
Effect of the MiR-99b and MiR-135b on peritoneal carcinomatosis and liver metastasis in colorectal cancer

Aziret, Mehmet; Eskiler, Gamze Guney; Cakar, Gozde Cakirsoy; Ozkan, Asuman Deveci; Ercan, Metin; Bilir, Cemil; Polat, Erdal; Kocer, Havva Belma; Yildirim, Ebru Kayra; Duman, Mustafa (ELSEVIER ESPANA, 2023)

Aim: This study aimed to evaluate the expression levels of miR-99b and miR-135b in peritoneal carcinoma and liver metastases associated with Colorectal Cancer (CRC), assess their association with the intracellular signaling ...
Effectiveness of 5-Fluorouracil and gemcitabine hydrochloride loaded iron-based chitosan-coated MIL-100 composite as an advanced, biocompatible, pH-sensitive and smart drug delivery system on breast cancer therapy

Resen, Ali K.; Atiroglu, Atheer; Atiroglu, Vesen; Eskiler, Gamze Guney; Aziz, Ismail H.; Kaleli, Suleyman; Ozacar, Mahmut (2022)

This study was planned to evolve the bioavailability and therapeutic efficiency of Gemcitabine (GEM) and 5Fluorouracil with decreased side effects using MIL-100 nano-composite as carrier. Impregnation approach was used for ...
Efficacy of 5-aminolevulinic acid-based photodynamic therapy in different subtypes of canine mammary gland cancer cells

Turna, Ozge; Baykal, Aslihan; Kucukkara, Elif Sozen; Ozten, Ozge; Ozkan, Asuman Deveci; Eskiler, Gamze Guney; Kamanli, Ali Furkan; Bilir, Cemil; Yildiz, Salih Zeki; Kaleli, Suleyman; Ucmak, Melih; Kasikci, Guven; Lim, Hyun Soo (SPRINGER LONDON LTD, 2021)

Canine mammary gland tumors (CMGTs) are heterogeneous disease and subclassified [sarcomas (S), carcinomas (C), and carcinosarcomas (CS)] according to histopathological differentiation. Photodynamic therapy (PDT) is a ...
Fabrication of dopamine conjugated with protein @metal organic framework for targeted drug delivery: A biocompatible pH-Responsive nanocarrier for gemcitabine release on MCF-7 human breast cancer cells

Abd Al-jabbar, Shatha; Atiroglu, Vesen; Hameed, Rana M.; Eskiler, Gamze Guney; Atiroglu, Atheer; Ozkan, Asuman Deveci; Ozacar, Mahmut (2022)

Metal-organic structures (MOF), modern extremely proliferous materials consisting of metal ions and organic coordinating molecules, has become a promising biomedical material because of its unusual features, including great ...
Investigation of LED-based photodynamic therapy efficiency on breast cancer cells

Kamanli, Ali Furkan; Yildiz, Mustafa Zahid; Ozyol, Ebru; Ozkan, Asuman Deveci; Kucukkara, Elif Sozen; Eskiler, Gamze Guney (SPRINGER LONDON LTD, 2021)

Photodynamic therapy (PDT) is based on special light source, photosensitizer (PS), and in the presence of oxygen. Different light sources have been used for PDT applications. Recent studies have focused on LED light sources ...
Optimization of 5-aminolevulinic acid-based photodynamic therapy protocol for breast cancer cells

Eskiler, Gamze Guney; Ozkan, Asuman Deveci; Kucukkara, Elif Sozen; Kamanli, Ali Furkan; Gunoglu, Busra; Yildiz, Mustafa Zahid (ELSEVIER, 2020)

Background: Photodynamic therapy (PDT) is a therapeutic strategy for the treatment of cancer. 5-aminolevulinic acid (5-ALA) as a precursor of the protoporphyrin IX (PpIX) has a great potential for PDT application. Although ...
Talazoparib nanoparticles for overcoming multidrug resistance in triple-negative breast cancer

Eskiler, Gamze Guney; Cecener, Gulsah; Egeli, Unal; Tunca, Berrin (WILEY, 2020)

Herein, we investigated efflux pumps-mediated talazoparib-resistance in the treatment of triple-negative breast cancer (TNBC). Furthermore, we produced a novel talazoparib-solid lipid nanoparticles (SLNs) and then explored ...
The Anticancer Potential of Chlorine Dioxide in Small-Cell Lung Cancer Cells

Yildiz, Salih Zeki; Bilir, Cemil; Eskiler, Gamze Guney; Bilir, Filiz (CUREUS INC, 2022)

Background Chlorine dioxide (ClO2) is an effective disinfectant consisting of oxygen, chloride, and potassium. Because of its high oxidative capacity, ClO2 exerts antimicrobial, antiviral, and antifungal effects. However, ...
The molecular mechanisms of vulpinic acid induced programmed cell death in melanoma

Yangin, Sevcan; Cansaran-Duman, Demet; Eskiler, Gamze Guney; Aras, Sumer (2022)

Backgrounds Malignant melanoma is an aggressive skin tumor with a rapidly increasing incidence and there is not yet a successful treatment strategy. Vulpinic acid (VA) is derived from secondary metabolites from lichen ...
The Predictive Role of MMP-2, MMP-9, TIMP-1 and TIMP-2 Serum Levels in the Complete Response of the Tumor to Chemotherapy in Breast Cancer Patients

Ozdemir, Kayhan; Zengin, Ismail; Eskiler, Gamze Guney; Kocer, Havva Belma; Ozkan, Asuman Deveci; Demiray, Tayfur; Sahin, Elif Ozozen (2022)

Objective We investigated the serum levels of MMPs and TIMPs in breast cancer (BC) patients to predict the response rate to/after treatment with or without neoadjuvant chemotherapy. BC is the most common cancer in women ...
The relationship between the efficacy of talazoparib and the functional toll-like receptors 3 and 9 in triple negative breast cancer

Eskiler, Gamze Guney; Ozkan, Asuman Deveci (2022)

Poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) induce cell death by inhibiting the repair of DNA strand breaks binding to PARP and regulate immune cells functions. Toll-like receptors (TLRs) mediate the tumor ...
The response of the canine mammary simple carcinoma and carcinosarcoma cells to 5-aminolaevulinic acid-based photodynamic therapy: An in vitro study

Eskiler, Gamze Guney; Turna, Ozge; Ozkan, Asuman Deveci; Baykal, Aslihan; Gurgen, Hazal Ozturk; Erk, Beyzanur; Armutak, Elif Ilkay; Lim, Hyun Soo (2022)

Backgrounds: Canine mammary gland tumors (CMGTs) are heterogeneous tumors and share many similar features with human breast cancer. Despite the improvement of current treatment options, new treatment modalities are required ...
Therapeutic potential of the PI3K inhibitor LY294002 and PARP inhibitor Talazoparib combination in BRCA-deficient triple negative breast cancer cells

Eskiler, Gamze Guney; Ozturk, Melek (2022)

Poly (ADP-ribose) polymerase (PARP) inhibitors provide a promising therapeutic strategy for triple-negative breast cancers (TNBCs) with BRCA1/2 mutation. However, acquire resistance mechanisms and genetic alterations limit ...
Usnic acid-induced programmed cell death in ovarian cancer cells

Colak, Betul; Cansaran-Duman, Demet; Eskiler, Gamze Guney; Foldes, Katalin; Yangin, Sevcan (2022)

Usnic acid (UA) is a secondary metabolite obtained by lichen species and exerts a significant anti-proliferative effect on different cancer cells. The current study aimed to determine the efficiency of UA on ovarian cancer ...