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Browsing Kimya / Chemistry by Author "Oktay Arslan"

Now showing items 1-6 of 6

Development of carbazole-bearing pyridopyrimidine-substituted urea/thiourea as polyphenol oxidase inhibitors: synthesis, biochemistry, and theoretical studies

Arleta Rifati Nixha; Adem Ergun; Nahit Gencer; Oktay Arslan; Arslan, Mustafa (TAYLOR & FRANCIS LTD, 2019)

Polyphenol oxidase (Tyrosinase, PPO) has received considerable attention, since it is the key enzyme in melanin biosynthesis. In this study, we investigated prepared novel carbazole-containing pyridopyrimidine-substituted ...
IMPACT OF CARBAZOLE P-LACTAM DERIVATIVES ON PARAOXONASE-1 ACTIVITY

Basak Gokce; Arlinda Bytyqi-Damoni; Genç Bilgiçli, Hayriye; Zengin, Mustafa; Nahit Gencer; Oktay Arslan (PARLAR SCIENTIFIC PUBLICATIONS (P S P), 2017)

Paraoxonase 1 (PON1) is an antioxidant enzyme associated with high-density lipoproteins (HDL). PON1 has the ability to inhibit lipid peroxides and to hydrolyze a wide variety of substrates such as esters, thioesters, ...
Synthesis and Biological Evaluation of New 4-Thiazolidinone Derivatives as Carbonic Anhydrase Inhibitors

Genç Bilgiçli, Hayriye; Busra Ceken; Cigdem Bilen; Zubeyde Sackes; Nahit Gencer; Oktay Arslan (BENTHAM SCIENCE PUBL LTD, 2017)

Conclusion: New aminoindane thiazolidinone derivatives have been designed, synthesized and evaluated as Carbonic Anhydrase Inhibitors. According to the results, these compounds can be conceivable as new candidates for the ...
Synthesis and carbonic anhydrase inhibitory properties of new spiroindoline-substituted sulphonamide compounds

Ozcan Gulec; Arslan, Mustafa; Nahit Gencer; Adem Ergun; Cigdem Bilen; Oktay Arslan (TAYLOR & FRANCIS LTD, 2017)

New spiroindoline-substituted sulphonamide compounds were synthesised and their inhibitory effects on the activity of purified human carbonic anhydrase I and II were evaluated. Human carbonic anhydrase isoenzymes (hCA-I ...
Synthesis and evaluation of new phthalazine substituted beta-lactam derivatives as carbonic anhydrase inhibitors

Nurcan Berber; Arslan, Mustafa; Cigdem Bilen; Zubeyde Sackes; Nahit Gencer; Oktay Arslan (MAIK NAUKA/INTERPERIODICA/SPRINGER, 2015)

A new series of phthalazine substituted beta-lactam derivatives were synthesized and their inhibitory effects on the activity of purified human carbonic anhydrase (hCA I and II) were evaluated. 2H-Indazolo[2,1-b]phthalazine-trione ...
Synthesis of carbazole bearing pyridopyrimidine-substituted sulfonamide derivatives and studies their carbonic anhydrase enzyme activity

Arleta Rifati-Nixha; Arslan, Mustafa; Nahit Gencer; Kubra Cikrikici; Basak Gokce; Oktay Arslan (WILEY, 2019)

The synthesis of carbazole containing pyridopyrimidine-substituted sulfonamide derivatives (3a-i) and their inhibitory effects on human carbonic anhydrase (hCA) I and II were studied. Spectral data and elemental analysis ...