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Browsing Kimya / Chemistry by Author "Cigdem Bilen"

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Synthesis and Biological Evaluation of New 4-Thiazolidinone Derivatives as Carbonic Anhydrase Inhibitors

Genç Bilgiçli, Hayriye; Busra Ceken; Cigdem Bilen; Zubeyde Sackes; Nahit Gencer; Oktay Arslan (BENTHAM SCIENCE PUBL LTD, 2017)

Conclusion: New aminoindane thiazolidinone derivatives have been designed, synthesized and evaluated as Carbonic Anhydrase Inhibitors. According to the results, these compounds can be conceivable as new candidates for the ...
Synthesis and carbonic anhydrase inhibitory properties of new spiroindoline-substituted sulphonamide compounds

Ozcan Gulec; Arslan, Mustafa; Nahit Gencer; Adem Ergun; Cigdem Bilen; Oktay Arslan (TAYLOR & FRANCIS LTD, 2017)

New spiroindoline-substituted sulphonamide compounds were synthesised and their inhibitory effects on the activity of purified human carbonic anhydrase I and II were evaluated. Human carbonic anhydrase isoenzymes (hCA-I ...
Synthesis and evaluation of N-heteroarylsubstituted triazolosulfonamides as carbonic anhydrase inhibitors

Ahmet Balci; Arslan, Mustafa; Arleta Rifati Nixha; Cigdem Bilen; Adem Ergun; Nahit Gencer (TAYLOR & FRANCIS LTD, 2015)

A new series of N-heteroarylsubstituted triazolosulfonamide compounds were synthesized and their inhibitory effects on the activity of purified human carbonic anhydrase (hCA) I and II were evaluated. Compounds (3 a-k) were ...
Synthesis and evaluation of new phthalazine substituted beta-lactam derivatives as carbonic anhydrase inhibitors

Nurcan Berber; Arslan, Mustafa; Cigdem Bilen; Zubeyde Sackes; Nahit Gencer; Oktay Arslan (MAIK NAUKA/INTERPERIODICA/SPRINGER, 2015)

A new series of phthalazine substituted beta-lactam derivatives were synthesized and their inhibitory effects on the activity of purified human carbonic anhydrase (hCA I and II) were evaluated. 2H-Indazolo[2,1-b]phthalazine-trione ...
Synthesis, Biological Activity and Structure-Activity Relationship of Novel Diphenylurea Derivatives Containing Tetrahydroquinoline as Carbonic Anhydrase I and II Inhibitors

Alparslan Atahan; Nahit Gencer; Cigdem Bilen; Emre Yavuz; Genç Bilgiçli, Hayriye; Sönmez, Fatih; Zengin, Mustafa; Mustafa Ceylan; Küçükislamoğlu, Mustafa (WILEY-V C H VERLAG GMBH, 2018)

A series of novel tetrahydroquinoline derivatives containing urea moiety was synthesized and their invitro inhibitory effects on the human carbonic anhydrase isoenzymes (hCA-I and hCA-II) were evaluated by using the CO2 ...