Browsing Kimya / Chemistry by Author "Adem Ergun"

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Development of carbazole-bearing pyridopyrimidine-substituted urea/thiourea as polyphenol oxidase inhibitors: synthesis, biochemistry, and theoretical studies

Arleta Rifati Nixha; Adem Ergun; Nahit Gencer; Oktay Arslan; Arslan, Mustafa (TAYLOR & FRANCIS LTD, 2019)

Polyphenol oxidase (Tyrosinase, PPO) has received considerable attention, since it is the key enzyme in melanin biosynthesis. In this study, we investigated prepared novel carbazole-containing pyridopyrimidine-substituted ...
Synthesis and carbonic anhydrase inhibitory properties of new spiroindoline-substituted sulphonamide compounds

Ozcan Gulec; Arslan, Mustafa; Nahit Gencer; Adem Ergun; Cigdem Bilen; Oktay Arslan (TAYLOR & FRANCIS LTD, 2017)

New spiroindoline-substituted sulphonamide compounds were synthesised and their inhibitory effects on the activity of purified human carbonic anhydrase I and II were evaluated. Human carbonic anhydrase isoenzymes (hCA-I ...
Synthesis and evaluation of N-heteroarylsubstituted triazolosulfonamides as carbonic anhydrase inhibitors

Ahmet Balci; Arslan, Mustafa; Arleta Rifati Nixha; Cigdem Bilen; Adem Ergun; Nahit Gencer (TAYLOR & FRANCIS LTD, 2015)

A new series of N-heteroarylsubstituted triazolosulfonamide compounds were synthesized and their inhibitory effects on the activity of purified human carbonic anhydrase (hCA) I and II were evaluated. Compounds (3 a-k) were ...