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Browsing by Subject "carbonic anhydrase"

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Genotoxicity evaluation of a new phthalazine substituted beta-lactam derivative in human lymphocytes

Aygun, Betul; Berber, Ahmet A.; Doganci, Merve A.; Berber, Nurcan; Sen, Selen; Yildiz, Esra; Aksoy, Huseyin (ACAD BRASILEIRA DE CIENCIAS, 2022)

The aim of present study, to evaluate the genotoxic potential of 1-(4-(3,3-dimethyl-1,6-dioxo-2,3,4,6,11,13-hexahydro-1H-indazolo[1,2b] phthalazine-13yl) phenyl)-2-phenylazetidine-3-yl-acetate which was synthesised assuming ...
Physical-chemical studies of new, versatile carbazole derivatives and zinc complexes: Their synthesis, investigation of in vitro inhibitory effects on alpha-glucosidase and human erythrocyte carbonic anhydrase I and II isoenzymes

Col, Sumeyye; Emirik, Mustafa; Alim, Zuhal; Baran, Arif (2022)

In this study, two novel zinc-phthalocyanine complexes (4a and 6a), containing carbazole rings, were investigated. The first phthalocyanine 4a has been synthesized from 4-(2-(3-acetyl-9H-carbazol-9-yl)ethoxy at the peripheral ...
Synthesis, characterisation, biological evaluation and in silico studies of sulphonamide Schiff bases

Durgun, Mustafa; Turkes, Cuneyt; Isik, Mesut; Demir, Yeliz; Sakli, Ali; Kuru, Ali; Guzel, Abdussamat; Beydemir, Sukru; Akocak, Suleyman; Osman, Sameh M.; AlOthman, Zeid; Supuran, Claudiu T. (TAYLOR & FRANCIS LTD, 2020)

Sulphonamides are biologically important compounds with low toxicity, many bioactivities and cost-effectiveness. Eight sulphonamide derivatives were synthesised and characterised by FT-IR, C-13 NMR, H-1 NMR, LC-MS and ...