Browsing by Subject "FDA"

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Identification of NEK7 inhibitors: structure based virtual screening, molecular docking, density functional theory calculations and molecular dynamics simulations

Aziz, Mubashir; Ejaz, Syeda Abida; Rehman, Hafiz Muzzammel; Alsubaie, A. S. A.; Mahmoud, K. H.; Siddique, Farhan; Al-Buriahi, M. S.; Alrowaili, Z. A. (TAYLOR & FRANCIS INC, )

NEK7 is a NIMA related-protein kinase that plays a crucial role in spindle assembly and cell division. Dysregulation of NEK7 protein leads to development and progression of different types of malignancies including colon ...