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Browsing by Subject "EXPRESSION"

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Anti-inflammatory effects of nobiletin on TLR4/TRIF/IRF3 and TLR9/IRF7 signaling pathways in prostate cancer cells

Deveci Ozkan, Asuman; Kaleli, Suleyman; Onen, Hacer Ilke; Sarihan, Mehmet; Guney Eskiler, Gamze; Kalayci Yigin, Aysel; Akdogan, Mehmet (TAYLOR & FRANCIS LTD, 2020)

Background: Toll-like receptors (TLRs) are often expressed in natural immune cells as well as in tumor cells. TLR4 exhibits both tumor promoting and tumor-suppressing roles and higher TLR9 expression is an important marker ...
Apelin, Omentin-1, and Vaspin in patients with essential hypertension: association of adipokines with trace elements, inflammatory cytokines, and oxidative damage markers

Cinemre, Fatma Behice Serinkan; Cinemre, Hakan; Bahtiyar, Nurten; Kahyaoglu, Behlul; Agac, Mustafa Tarik; Shundo, Harika; Sevinc, Leyla; Aydemir, Birsen (SPRINGER LONDON LTD, 2021)

Background Hypertension (HT) is a disease associated with endothelial dysfunction which is related to some adipokines and pro- and anti-inflammatory cytokines. Aims Our aim was to investigate roles of apelin, omentin-1, ...
Cardiac toxicity of acrolein exposure in embryonic zebrafish (Danio rerio)

Arman, Sezgi; Isisag Ucuncu, Sema (SPRINGER HEIDELBERG, 2020)

Acrolein is a widely distributed pollutant produced from various sources such as industrial waste, organic combustion, and power plant emissions. It is also intentionally released into irrigation canals to control invasive ...
Clinical Evaluation on Non-Functional Invasive Hypophysis Adenomas

Gokosmanoglu, Feyzi; Varim, Ceyhun; Oztop, Kenan Evren (KNOWLEDGE E, 2020)

Background: There are ongoing studies to predetermine non-functional invasive pituitary adenomas that may show aggressive behavior. Our aim is to discuss whether there is a relationship between the immunohistochemical ...
ENHANCED EFFICACY OF RESVERATROL-LOADED SILVER NANOPARTICLE IN ATTENUATING SEPSIS-INDUCED ACUTE LIVER INJURY: MODULATION OF INFLAMMATION, OXIDATIVE STRESS, AND SIRT1 ACTIVATION

Üstündag, H; Kalindemirtas, FD; Doganay, S; Demir, Ö; Kurt, N; Huyut, MT; Özgeris, B; Kariper, IA (2023)

Sepsis-induced acute liver injury is a life-threatening condition involving inflammation, oxidative stress, and endothelial dysfunction. In the present study, the preventive effects of resveratrol (RV) alone and RV-loaded ...
Erythropoietin shows gender dependent positive effects on social deficits, learning/memory impairments, neuronal loss and neuroinflammation in the lipopolysaccharide induced rat model of autism

Solmaz, Volkan; Erdogan, Mumin Alper; Alnak, Alper; Meral, Ayfer; Erbas, Oytun (CHURCHILL LIVINGSTONE, 2020)

We aimed to evaluate the effects of EPO in the lipopolysaccharide (LPS) induced rat model of autism in terms of social deficits, learning and memory impairments, as well as their neurochemical correlates. Sixteen female ...
HLA class I and class II polymorphism in mitral chordae tendineae rupture

Vatan, MB; Yigin, AK; Akdemir, R; Agac, MT; Vatan, A; Karacan, K (2023)

Objective: Mitral chordae tendinea rupture (MCTR) is a progressive condition which frequently results in severe mitral regurgitation. Several studies have suggested that genetic susceptibility to various valvular heart ...
Retinal nerve fiber layer and ganglion cell complex thickness in diabetic smokers without diabetic retinopathy

Gündogdu, KO; Dogan, E; Çelik, E; Alagöz, G (2023)

PurposeTo compare the thickness of the retinal nerve fiber layer (RNFL) and macular ganglion cell-inner plexiform layer (GC-IPL) in smoker and nonsmoker diabetics without diabetic retinopathy.Materials and MethodsPatients ...
Salivary and serum concentrations of monocyte chemoattractant protein-1, macrophage inhibitory factor, and fractalkine in relation to rheumatoid arthritis and periodontitis

Yilmaz, Dogukan; Gonullu, Emel; Gursoy, Mervi; Kononen, Eija; Gursoy, Ulvi Kahraman (WILEY, 2021)

Background: Monocyte chemoattractant protein-1 (MCP-1), macrophage migration inhibitory factor (MIF), and fractalkine are chemokines that are expressed by a variety of cell types to regulate macrophage inflammatory response. ...
Salivary human beta-defensins and cathelicidin levels in relation to periodontitis and type 2 diabetes mellitus

Yilmaz, Dogukan; Topcu, Ali Orkun; Akcay, Emine Ulku; Altindis, Mustafa; Gursoy, Ulvi Kahraman (TAYLOR & FRANCIS LTD, 2020)

Objective: Type 2 diabetes mellitus (T2DM) is a well-defined risk factor of periodontitis and it can affect expression of human beta-defensins (hBDs) and cathelicidin (LL-37) as well. The aim of the present study was to ...
Sclerosing angiomatoid nodular transformation presenting with thrombocytopenia after laparoscopic splenectomy - Case report and systematic review of 230 patients

Aziret, Mehmet; Yilmaz, Fahri; Kalpakci, Yasin; Subasi, Ozkan; Senturk, Adem; Karaman, Kerem; Ercan, Metin (ELSEVIER SCI LTD, 2020)

Background: Sclerosing angiomatoid vascular transformation (SANT) is a rare vascular disease of the spleen, which is difficult to diagnose due to its pre-intervention appearance of malignancy. Case Report: An 85-year-old ...
Serum kallistatin level is decreased in women with preeclampsia

Gueralp, Onur; Tuten, Nevin; Gok, Koray; Hamzaoglu, Kubra; Bulut, Huri; Schild-Suhren, Meike; Malik, Eduard; Tuten, Abdullah (WALTER DE GRUYTER GMBH, 2021)

Objectives: To evaluate the serum levels of the senile proteinase inhibitor kallistatin in women with preeclampsia (PE). Methods: The clinical and laboratory parameters of 55 consecutive women with early-onset PE (EOPE) ...
Stimulating effects of vardenafil, tadalafil, and udenafil on vascular endothelial growth factor, angiogenesis, vitamin D-3, bone morphogenic proteins in ovariectomized rats

Huyut, Zubeyir; Alp, Hamit Hakan; Bakan, Nuri; Yildirim, Serkan; Sekeroglu, Mehmet Ramazan (TAYLOR & FRANCIS LTD, )

Objective: This study investigated the effect of vardenafil, tadalafil, and udenafil from phosphodiesterase-5 inhibitors (PDE-5Is) on bone morphogenic-protein (BMP)2 and 4 levels, along with angiogenesis in ovariectomized ...
Zaprinast and avanafil increase the vascular endothelial growth factor, vitamin D-3, bone morphogenic proteins 4 and 7 levels in the kidney tissue of male rats applied the glucocorticoid

Huyut, Zubeyir; Bakan, Nuri; Akbay, Halil Ibrahim; Yildirim, Serkan; Sekeroglu, Mehmet Ramazan (TAYLOR & FRANCIS LTD, )

Objective: This study investigated effect of zaprinast and avanafil on vascular endothelial growth factor (VEGF), bone morphogenic protein (BMP) 4 and 7, and vitamin D-3 levels against the negative effect of dexamethazone. ...