DSpace Home
→
Browsing by Subject

Browsing by Subject "Breast cancer"

Now showing items 1-8 of 8

A New Prognostic Index in Young Breast Cancer Patients

Demir, Hacer; Demirci, Ayse; Eren, Saliha Karagoz; Beypinar, Ismail; Davarci, Sena Ece; Baykara, Meltem (COLL PHYSICIANS & SURGEONS PAKISTAN, 2022)

Objective:To evaluate the prognostic role of pan immune-inflammation value (PIV) in young breast cancer patients. Study Design: Descriptive study. Place and Duration of Study: Department of Medical Oncology, Afyon University ...
Effectiveness of 5-Fluorouracil and gemcitabine hydrochloride loaded iron-based chitosan-coated MIL-100 composite as an advanced, biocompatible, pH-sensitive and smart drug delivery system on breast cancer therapy

Resen, Ali K.; Atiroglu, Atheer; Atiroglu, Vesen; Eskiler, Gamze Guney; Aziz, Ismail H.; Kaleli, Suleyman; Ozacar, Mahmut (2022)

This study was planned to evolve the bioavailability and therapeutic efficiency of Gemcitabine (GEM) and 5Fluorouracil with decreased side effects using MIL-100 nano-composite as carrier. Impregnation approach was used for ...
Evaluation of the antioxidative and genotoxic effects of sodium butyrate on breast cancer cells

Yuksel, Burcu; Ozkan, Asuman Deveci; Aydin, Duygu; Betts, Zeynep (ELSEVIER, 2022)

Oncogenic stimulation shows a rise in reactive oxygen species (ROS), and ROS can eventually induce carcinogenesis by causing DNA damage. In this context, this study aims to evaluate some biochemical and genotoxic changes ...
Fabrication of dopamine conjugated with protein @metal organic framework for targeted drug delivery: A biocompatible pH-Responsive nanocarrier for gemcitabine release on MCF-7 human breast cancer cells

Abd Al-jabbar, Shatha; Atiroglu, Vesen; Hameed, Rana M.; Eskiler, Gamze Guney; Atiroglu, Atheer; Ozkan, Asuman Deveci; Ozacar, Mahmut (2022)

Metal-organic structures (MOF), modern extremely proliferous materials consisting of metal ions and organic coordinating molecules, has become a promising biomedical material because of its unusual features, including great ...
In vitro chemo-protective effect of Eisenia foetida coelomic fluid against histone deacetylase inhibitor-induced oxidative toxicity in breast cancer cells

Ozkan, Asuman Deveci; Alimudin, Janiah; Kilciler, Yasemin; Yuksel, Burcu; Aksoy, Ozlem; Betts, Zeynep (2022)

Developing new drugs from natural products is important for therapeutic effects to minimise tissue toxicity of drugs used in cancer treatment. Eisenia foetida is a worm with a double transport system consisting of coelomic ...
The effect of mesenchymal stromal cells in the microenvironment on cancer development

Saglam-Ucar, Ozlem; Degirmenci, Irfan; Halbutogullari, Zehra Seda; Posteki, Gokhan; Subasi-Demirci, Cansu; Erman, Gulay; Karaoz, Erdal; Utkan, N. Zafer (2022)

Inflammatory signals secreted from the tumor microenvironment are thought to promote tumor growth and survival. It has been reported that stromal cells in the tumor microenvironment have similar characteristics to ...
The Predictive Role of MMP-2, MMP-9, TIMP-1 and TIMP-2 Serum Levels in the Complete Response of the Tumor to Chemotherapy in Breast Cancer Patients

Ozdemir, Kayhan; Zengin, Ismail; Eskiler, Gamze Guney; Kocer, Havva Belma; Ozkan, Asuman Deveci; Demiray, Tayfur; Sahin, Elif Ozozen (2022)

Objective We investigated the serum levels of MMPs and TIMPs in breast cancer (BC) patients to predict the response rate to/after treatment with or without neoadjuvant chemotherapy. BC is the most common cancer in women ...
The prognostic and predictive values of differential expression of exosomal receptor tyrosine kinases and associated with the PI3K/AKT/mTOR signaling in breast cancer patients undergoing neoadjuvant chemotherapy

Guney Eskiler, Gamze; Kazan, Nur; Haciefendi, Ayten; Deveci Ozkan, Asuman; Ozdemir, Kayhan; Ozen, Mirac; Kocer, Havva Belma; Yilmaz, Fahri; Kaleli, Suleyman (2022)

Purpose Cancer cell-derived exosomes are the mediator of the tumor microenvironment and the molecular content of exosomes presents a promising prognostic or predictive marker in tumor progression and the treatment response ...