Browsing by Author "Kaleli, Suleyman/0000-0002-6043-2521"

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Effectiveness of 5-Fluorouracil and gemcitabine hydrochloride loaded iron-based chitosan-coated MIL-100 composite as an advanced, biocompatible, pH-sensitive and smart drug delivery system on breast cancer therapy

Resen, Ali K.; Atiroglu, Atheer; Atiroglu, Vesen; Eskiler, Gamze Guney; Aziz, Ismail H.; Kaleli, Suleyman; Ozacar, Mahmut (2022)

This study was planned to evolve the bioavailability and therapeutic efficiency of Gemcitabine (GEM) and 5Fluorouracil with decreased side effects using MIL-100 nano-composite as carrier. Impregnation approach was used for ...
The prognostic and predictive values of differential expression of exosomal receptor tyrosine kinases and associated with the PI3K/AKT/mTOR signaling in breast cancer patients undergoing neoadjuvant chemotherapy

Guney Eskiler, Gamze; Kazan, Nur; Haciefendi, Ayten; Deveci Ozkan, Asuman; Ozdemir, Kayhan; Ozen, Mirac; Kocer, Havva Belma; Yilmaz, Fahri; Kaleli, Suleyman (2022)

Purpose Cancer cell-derived exosomes are the mediator of the tumor microenvironment and the molecular content of exosomes presents a promising prognostic or predictive marker in tumor progression and the treatment response ...