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Browsing by Author "Ilhami Gulcin"

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Aminopyrazole-substituted metallophthalocyanines: Preparation, aggregation behavior, and investigation of metabolic enzymes inhibition properties

Güzel, Emre; Umit M. Kocyigit; Baris S. Arslan; Mehmet Atas; Parham Taslimi; Faik Gokalp; Nebioğlu, Mehmet; Şişman, İlkay; Ilhami Gulcin (WILEY-V C H VERLAG GMBH, 2019)

The synthesis, characterization, aggregation behavior, theoretical studies, and investigation of antimicrobial, antidiabetic, and anticholinergic properties of 4-(2-(5-amino-4-(4-bromophenyl)-3-methyl-1H-pyrazol-1-yl)eth ...
Novel carvacrol based new oxypropanolamine derivatives: Design, synthesis, characterization, biological evaluation, and molecular docking studies

Arlinda Bytyqi-Damoni; Ali Kestane; Parham Taslimi; Burak Tuzun; Zengin, Mustafa; Genç Bilgiçli, Hayriye; Ilhami Gulcin (ELSEVIER, 2020)

Carvacrol, as a natural product used for many years in the treatment of various diseases, therefore it was chosen as the starting compound for this study. Novel carvacrol based new oxypropanolamine derivatives were synthesized ...
Novel eugenol bearing oxypropanolamines: Synthesis, characterization, antibacterial, antidiabetic, and anticholinergic potentials

Genç Bilgiçli, Hayriye; Ali Kestane; Parham Taslimi; Karabay, Oğuz; Arlinda Bytyqi-Damoni; Zengin, Mustafa; Ilhami Gulcin (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2019)

Five oxypropanol amine derivatives that four of them are novel have been synthesized with high yields and practical methods. in vitro antibacterial susceptibility of Acinetobacter baumannii, Pseudomonas aeruginosa, Escherichia ...
Novel eugenol bearing oxypropanolamines: Synthesis, characterization, antibacterial, antidiabetic, and anticholinergic potentials

Genç Bilgiçli, Hayriye; Ali Kestane; Parham Taslimi; Karabay, Oğuz; Arlinda Bytyqi-Damoni; Zengin, Mustafa; Ilhami Gulcin (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2019)

Five oxypropanol amine derivatives that four of them are novel have been synthesized with high yields and practical methods. in vitro antibacterial susceptibility of Acinetobacter baumannii, Pseudomonas aeruginosa, Escherichia ...
Novel thymol bearing oxypropanolamine derivatives as potent some metabolic enzyme inhibitors - Their antidiabetic, anticholinergic and antibacterial potentials

Zengin, Mustafa; Genç Bilgiçli, Hayriye; Parham Taslimi; Ali Kestane; Güçlü, Ertuğrul; Öğütlü, Aziz; Karabay, Oğuz; Ilhami Gulcin (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2018)

A series of classical and newly synthesized thymol bearing oxypropanolamine compounds were synthesized and characterized. Their in vitro antibacterial activity on A. baumannii, P. aeruginosa, E. coli and S. aureus strains ...
Novel thymol bearing oxypropanolamine derivatives as potent some metabolic enzyme inhibitors - Their antidiabetic, anticholinergic and antibacterial potentials

Zengin, Mustafa; Genç Bilgiçli, Hayriye; Parham Taslimi; Ali Kestane; Güçlü, Ertuğrul; Öğütlü, Aziz; Karabay, Oğuz; Ilhami Gulcin (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2018)

A series of classical and newly synthesized thymol bearing oxypropanolamine compounds were synthesized and characterized. Their in vitro antibacterial activity on A. baumannii, P. aeruginosa, E. coli and S. aureus strains ...
SAR Evaluation of Disubstituted Tacrine Analogues as Promising Cholinesterase and Carbonic Anhydrase Inhibitors

Salih Okten; Makbule Ekiz; Tutar, Ahmet; Burcu Butun; Umit Muhammet Kocyigit; Gulacti Topcu; Ilhami Gulcin (ASSOC PHARMACEUTICAL TEACHERS INDIA, 2019)

Background: The inhibition of both hydrolysis products of acetylcholine (ACh), Acetylcholinesterase (AChE) and Butyrylcholinesterase (BChE), is essential for successful treatment of Alzhemier patients. Objectives: This ...
Synthesis, characterization, biological evaluation, and molecular docking studies of some piperonyl-based 4-thiazolidinone derivatives

Genç Bilgiçli, Hayriye; Parham Taslimi; Busra Akyuz; Burak Tuzun; Ilhami Gulcin (WILEY-V C H VERLAG GMBH, 2020)

Heterocyclic compounds are of particular importance among pharmacologically active compounds. In this study, some piperonyl-based 4-thiazolidinone derivatives (2a-i) were synthesized and characterized by spectroscopic ...
Synthesis, characterization, biological evaluation, and molecular docking studies of some piperonyl-based 4-thiazolidinone derivatives

Genç Bilgiçli, Hayriye; Parham Taslimi; Busra Akyuz; Burak Tuzun; Ilhami Gulcin (WILEY-V C H VERLAG GMBH, 2019)

Heterocyclic compounds are of particular importance among pharmacologically active compounds. In this study, some piperonyl-based 4-thiazolidinone derivatives (2a-i) were synthesized and characterized by spectroscopic ...
Synthesis, characterization, crystal structures, theoretical calculations and biological evaluations of novel substituted tacrine derivatives as cholinesterase and carbonic anhydrase enzymes inhibitors

Salih Okten; Makbule Ekiz; Umit Muhammet Kocyigit; Tutar, Ahmet; Çelik, İsmail; Mehmet Akkurt; Faik Gokalp; Parham Taslimi; Ilhami Gulcin (ELSEVIER SCIENCE BV, 2019)

The six and seven hydrocycle membered disilylanilino acridine (tacrine) analogues (9-11) were synthesized by one-pot procedures. The structures of novel silyl tacrine derivatives were characterized by NMR spectroscopy, ...