DSpace Home
→
Fakülteler / Faculties
→
Tıp Fakültesi
→
Dahili Tıp Bilimleri / Internal Medıcal Scıences
→
Makale Koleksiyonu
→
Browsing Makale Koleksiyonu by Author

Browsing Makale Koleksiyonu by Author "Bilir, Cemil"

Now showing items 1-12 of 12

An individual patient-data meta-analysis of metronomic oral vinorelbine in metastatic non-small cell lung cancer

Jean-Louis Pujol; Amandine Coffy; Andrea Camerini; Athanasios Kotsakis; Manlio Mencoboni; Milena Gusella; Felice Pasini; Aldo Pezzuto; Giuseppe Luigi Banna; Bilir, Cemil; Epaminontas Samantas; Fabrice Barlesi; Benoit Roch; Aude Guillou; Jean-Pierre Daures (PUBLIC LIBRARY SCIENCE, 2019)

MOV is an active and well-tolerated chemotherapy in metastatic NSCLC and is a manageable therapy in frail patients.
Efficacy of metronomic vinorelbine in elderly patients with advanced non-small-cell lung cancer and poor performance status

Bilir, Cemil; S. Durak; B. Kizilkaya; Hacıbekiroğlu, İlhan; E. Nayir; H. Engin (MULTIMED INC, 2017)

Conclusions Metronomic vinorelbine had an acceptable efficacy and safety profile in elderly patients with multiple comorbidities who had been diagnosed with advanced nsclc. Metronomic vinorelbine could be a treatment option ...
IL-6 mediated JAK/STAT3 signaling pathway in cancer patients with cachexia

Guney G. Eskiler; Güney Eskiler, Gamze; E. Bezdegumeli; Z. Ozman; Deveci A. Ozkan; Deveci Özkan, Asuman; Bilir, Cemil; Bilir, Cemil; B. N. Kucukakca; M. N. Ince; A. Y. Men; O. Aktas; Y. E. Horoz; D. Akpinar (COMENIUS UNIV, 2019)

CONCLUSION: STAT3 may be considered as a therapeutic target for cachectic patients with gastric, lung and breast cancer. Furthermore, IL-6 mediates STAT3 activation in cachectic gastric and breast cancer patients (Tab. 5, ...
Inhibition of TLR4/TRIF/IRF3 Signaling Pathway by Curcumin in Breast Cancer Cells

Güney Eskiler, Gamze; Deveci Özkan, Asuman; Kaleli, Süleyman; Bilir, Cemil (CANADIAN SOC PHARMACEUTICAL SCIENCES, 2019)

Purpose: Toll-like receptor 4 (TLR4) is over-expressed in breast tumors and thus contributing to the tumor progression and metastasis. Natural products have drawn attention in cancer immunotherapy due to their various ...
Is Change in Hemoglobin Level a Predictive Biomarker of Tyrosine Kinase Efficacy in Metastatic Renal Cell Carcinoma? A Turkish Oncology Group Study

Bilir, Cemil; Ibrahim Yildiz; Ahmet Bilici; Mahmut Ucar; Veli Berk; Yasar Yildiz; Ozan Yazici; Goksen Inanc Imamoglu; Nuri Karadurmus; Kezban Nur Pilanci; Erkan Arpaci; Ozgur Tanriverdi; Ebru Karci; Suleyman Temiz; Erdinc Nayir; Esin Oktay; Pinar Dal; Ibrahim Petekkaya; Varım, Ceyhun; Cinemre, Hakan (TAYLOR & FRANCIS INC, 2017)

Background: There are insufficient predictive markers for renal cell carcinoma (RCC). Methods: A total of 308 metastatic RCC patients were analyzed retrospectively. Results: The increased hemoglobin (Hb) group had significantly ...
Is there a difference in mad honey poisoning between geriatric and non-geriatric patient groups?

Yaylacı, Selçuk; O. Ayyildiz; Aydın, Engin; A. Osken; F. Karahalil; Varım, Ceyhun; M. V. Demir; A. B. Genc; S. Sahinkus; Can, Yusuf; Kocayiğit, İbrahim; Bilir, Cemil (VERDUCI PUBLISHER, 2015)

CONCLUSIONS: The mad honey poisoning should be considered in previously healthy patients with unexplained symptoms of bradycardia, hypotension, and atrioventricular block. Therefore, diet history should carefully be obtained ...
MDM2 antagonist-loaded targeted micelles in combination with doxorubicin: effective synergism against human glioblastoma via p53 re-activation

C. Sarisozen; Y. Tan; J. Liu; Bilir, Cemil; L. Shen; N. Filipczak; T. M. Porter; V. P. Torchilin (TAYLOR & FRANCIS LTD, 2019)

p53, The tumour suppressor protein encoded by P53 gene, is the most commonly altered protein in the human malignancies. MDM2 controls the p53 activity through an autoregulatory feedback loop. p53 activates the expression ...
Prognostic Value of Pre- and Posttreatment PET/CT Parameters in Patients Diagnosed with Advanced Stage NSCLC

Bilir, Cemil; Baran Yusufoglu; Bayram Kizilkaya; Huseyin Engin (BENTHAM SCIENCE PUBL LTD, 2018)

Conclusion: This study showed that the posttreatment WB TLG is significantly associated with oncologic outcomes. The metabolic changes in the mediastinal lymph nodes, as shown by the SUVmax and TLG, have a prognostic value ...
Prognostic Value of Volumetric Parameters of PET-CT With Stage IIIB-IV Non-Small Cell Lung Cancer

B. Yusufoglu; Bilir, Cemil (SPRINGER, 2016)
Synergistic Effects of Nobiletin and Sorafenib Combination on Metastatic Prostate Cancer Cells

Güney Eskiler, Gamze; Deveci Özkan, Asuman; Bilir, Cemil; Kaleli, Süleyman (ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 2019)

Objective: Herein we, for the first time, investigated a potential synergistic effect of nobiletin (NOB) and sorafenib (SOR) on PC-3 prostate cancer and HUVEC control cell lines.Methods: In order to determine the cytotoxic ...
Tendency of cancer patients and their relatives to use Internet for health-related searches: Turkish Oncology Group (TOG) Study

Erdinc Nayir; Ozgur Tanriverdi; Yusuf Karakas; Saadettin Kilickap; Nazim Serdar Turhal; Nilufer Avci; Kerem Okutur; Dogan Koca; Dilek Erdem; Huseyin Abali; Deniz Yamac; Bilir, Cemil; Turgut Kacan (ZERBINIS MEDICAL PUBL, 2016)

Conclusion: Cancer patients and their relatives showed a higher tendency to use health-related internet information which may mislead them, and can result in treatment incompliance. Health professionals should offer ...
The effects of zoledronic acid on ECG: a prospective study on patients with bone metastatic cancer

Derya Demirtas; Bilir, Cemil; Abdullah Orhan Demirtas; Huseyin Engin (CIC EDIZIONI INT, 2017)

Conclusion. There were no significant alterations in ECG in the acute period, indicated that ZA had no arrhythmia potential in the early period in patients with no underlying cardiac disease. However: patients receiving ...