Reversible bilateral ototoxicity in a patient with chronic hepatitis B during peginterferon alpha-2a treatment

Hasan Tahsin Gozdas; Karabay, Oğuz

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dc.contributor.authors	Gozdas, HT; Karabay, O;
dc.date.accessioned	2020-02-27T08:44:41Z
dc.date.available	2020-02-27T08:44:41Z
dc.date.issued	2015
dc.identifier.citation	Gozdas, HT; Karabay, O; (2015). Reversible bilateral ototoxicity in a patient with chronic hepatitis B during peginterferon alpha-2a treatment. INDIAN JOURNAL OF PHARMACOLOGY, 47, 122-121
dc.identifier.issn	0253-7613
dc.identifier.uri	https://doi.org/10.4103/0253-7613.150377
dc.identifier.uri	https://hdl.handle.net/20.500.12619/66829
dc.description.abstract	Peginterferon alpha-2a (PEG IFN -2a) is frequently used in chronic hepatitis B (CHB)treatment. Numerous adverse events can be noted during this therapy such as flu-like disease, rash, weight loss and depression. However, PEG IFN -2a related ototoxicity seems to be an uncommon entity. Ototoxicity can be detected objectively by audiometry. In this paper, we present a case of CHB who developed reversible bilateral ototoxicity during PEG IFN -2a treatment. Due to ototoxicity detected objectively by audiogram, treatment was ceased at sixth month and ototoxicity completely recovered one month after stopping the drug.
dc.language	English
dc.publisher	WOLTERS KLUWER MEDKNOW PUBLICATIONS
dc.subject	Pharmacology & Pharmacy
dc.title	Reversible bilateral ototoxicity in a patient with chronic hepatitis B during peginterferon alpha-2a treatment
dc.type	Article
dc.identifier.volume	47
dc.identifier.startpage	121
dc.identifier.endpage	122
dc.contributor.department	Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü
dc.contributor.saüauthor	Karabay, Oğuz
dc.relation.journal	INDIAN JOURNAL OF PHARMACOLOGY
dc.identifier.wos	WOS:000349144300024
dc.identifier.doi	10.4103/0253-7613.150377
dc.identifier.eissn	1998-3751
dc.contributor.author	Hasan Tahsin Gozdas
dc.contributor.author	Karabay, Oğuz