Açık Akademik Arşiv Sistemi

Production of (R)-1-phenylethanols Through Bioreduction of Acetophenones by a New Fungus Isolate Trichothecium roseum

Production of (R)-1-phenylethanols Through Bioreduction of Acetophenones by a New Fungus Isolate Trichothecium roseum

Taşkın, Mehmet Fatih; Kurbanoğlu, Namudar İzzet; Kılıç, Harun
URI: https://doi.org/10.1002/chir.20775
https://hdl.handle.net/20.500.12619/66304
Date: 2010

Abstract:

A total of 120 fungal strains were isolated from soil samples and evaluated in the bioreduction of substituted acetophenones to the corresponding (R)-alcohols. Among these strains, isolate Trichothecium roseum EBK-18 was highly effective in the production of (R)-alcohols with excellent enantioselectivity (ee > 99%). Gram scale preparation of (R)-1-phenylethanol is reported. Chirality 22:543-547, 2010. (C) 2009 Wiley-Liss, Inc.

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