Açık Akademik Arşiv Sistemi

The association of lectin-like oxidized LDL receptor 1 (LOX-1) K167N and 3'UTR188CT polymorphisms with maternal plasma soluble LOX-1 levels and preeclampsia risk in Turkish population

The association of lectin-like oxidized LDL receptor 1 (LOX-1) K167N and 3'UTR188CT polymorphisms with maternal plasma soluble LOX-1 levels and preeclampsia risk in Turkish population

Abdullah Tuten; Aydemir, Birsen; Mahmut Oncul; Ali Riza Kiziler; Abdullah Serdar Acikgoz; Gulcan Guntas Korkmaz; Volkan Sozer; Uzun, Hüseyin
URI: https://doi.org/10.1007/s00404-014-3457-4
https://hdl.handle.net/20.500.12619/65361
Date: 2015

Abstract:

Our findings indicate that higher plasma sLOX-1 and oxLDL concentrations, and the LOX-1 3'UTR188C > T and LOX-1 K167N gene polymorphisms were significantly associated with risk of developing preeclampsia. Plasma sLOX-1 may be a potential therapeutic target in the treatment of preeclampsia.

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