Production of (R)-3 '-fluorophenylethan-1-ol by Trichothecium roseum isolate in a laboratory scale bioreactor

Abstract

CONCLUSION: An important chiral intermediate for the pharmaceutical industry using T. roseum EBK-11 in submerged culture containing RHP from waste material was produced up to gram scale with excellent ee (99%). In this work, T. roseum fungus was used for the first time as a biocatalyst for efficient production of a chiral alcohol. (C) 2009 Society of Chemical Industry