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Production of (S)-(-)-1-(1'-Napthyl) Ethanol by Rhodotorula glutinis Isolate Using Ram Horn Peptone

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dc.contributor.authors Kurbanoglu, EB; Zilbeyaz, K; Kurbanoglu, NI; Taskin, M; Kilic, H;
dc.date.accessioned 2020-02-25T11:41:13Z
dc.date.available 2020-02-25T11:41:13Z
dc.date.issued 2008
dc.identifier.citation Kurbanoglu, EB; Zilbeyaz, K; Kurbanoglu, NI; Taskin, M; Kilic, H; (2008). Production of (S)-(-)-1-(1'-Napthyl) Ethanol by Rhodotorula glutinis Isolate Using Ram Horn Peptone. TURKISH JOURNAL OF CHEMISTRY, 32, 692-685
dc.identifier.issn 1300-0527
dc.identifier.uri https://hdl.handle.net/20.500.12619/48250
dc.description.abstract The bioreduction of 1-acetonaphthone 1 by locally isolated Rhodotorula glutinis strains using ram horn peptone (RHP) gave (S)-(-)-1-(1'-naphthyl) ethanol ( 2), an important pharmaceutical intermediate. R. glutinis strains were isolated from the water of fermented Salix leaves. Optimum fermentation conditions for the production of 2 were 200 rpm, 32 degrees C, and pH 6.5. The production of 2 with excellent enantiomeric excess (> 99%), and good conversion (100%) and yield (78%) under optimum conditions was achieved up to preparative scale via a fermenter. Wide temperature, pH, time, and agitation ranges did not affect the enantiomeric excess (ee) of the bioreduction product. A simple process for the isolation of R. glutinis was also developed.
dc.language English
dc.publisher SCIENTIFIC TECHNICAL RESEARCH COUNCIL TURKEY-TUBITAK
dc.subject Engineering
dc.title Production of (S)-(-)-1-(1'-Napthyl) Ethanol by Rhodotorula glutinis Isolate Using Ram Horn Peptone
dc.type Article
dc.identifier.volume 32
dc.identifier.startpage 685
dc.identifier.endpage 692
dc.contributor.department Sakarya Üniversitesi/Eğitim Fakültesi/Matematik Ve Fen Bilimleri Eğitimi Bölümü
dc.contributor.saüauthor Kurbanoğlu, Namudar İzzet
dc.contributor.saüauthor Taşkın, Mehmet Fatih
dc.contributor.saüauthor Kılıç, Harun
dc.relation.journal TURKISH JOURNAL OF CHEMISTRY
dc.identifier.wos WOS:000262864700004
dc.contributor.author Kurbanoğlu, Namudar İzzet
dc.contributor.author Taşkın, Mehmet Fatih
dc.contributor.author Kılıç, Harun


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