Determination of Some Metal Levels in Multivitamin Tablets by ICP-OES after Different Digestion Methods

Abstract

The aim of this study is to determine the quantities of Fe, Cu, Mn and Zn, the common trace metals contained in Supradyn and Pharmaton multivitamin tablets used widely by the consumers and compare them with the reference values given in their prospectus. For this purpose, three different methods namely dry, wet and microwave digestion methods were used. After digestion process, the concentrations of the micro metals contained in both trade preparations were determined using ICP-OES. Recovery values obtained as a result of the analysis were within 85-115% ranges. It was observed that there is no significant difference between the data obtained from the chemical analysis applied for both preparations and the reference values. Furthermore, SPSS statistical analysis software was used to determine if there is a significant statistical difference among the measurements made using three different digestion methods. Statistical results showed that there is not a significant difference among the digestion methods applied.