Browsing Makale Koleksiyonu by Author "Arabaci, G; Yi, T; Fu, H; Porter, ME; Beebe, KD; Pei, DH;"

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alpha-Bromoacetophenone derivatives as neutral protein tyrosine phosphatase inhibitors: Structure-activity relationship

Arabacı, Gülnur; T Yi; H Fu; Me Porter; Kd Beebe; Dh Pei (PERGAMON-ELSEVIER SCIENCE LTD, 2002)

A series of α-haloacetophenone derivatives was tested for inhibition of protein tyrosine phosphatases SHP-1 and PTP1B. The results show that the bromides are much more potent than the corresponding chlorides, whereas the ...