Açık Akademik Arşiv Sistemi

Ovarian follicle structure of Zebrafish (Danio rerio Hamilton) after poly(2-ethyl-2-oxazoline) exposure

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dc.contributor.authors Yon, ND; Olgun, U; Akbulut, C;
dc.date.accessioned 2020-01-20T09:03:55Z
dc.date.available 2020-01-20T09:03:55Z
dc.date.issued 2016
dc.identifier.citation Yon, ND; Olgun, U; Akbulut, C; (2016). Ovarian follicle structure of Zebrafish (Danio rerio Hamilton) after poly(2-ethyl-2-oxazoline) exposure. INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY, 54, 834-829
dc.identifier.issn 0019-5189
dc.identifier.uri https://hdl.handle.net/20.500.12619/33325
dc.identifier.uri http://nopr.niscair.res.in/handle/123456789/38284
dc.description.abstract Poly(2-oxazoline)s have been widely known for their biomedical applications. They mimic natural systems and are generally used as liposomes, drug and gene delivery modules and also as pseudopeptides. In this study, effects of different doses (10 and 50 mg/L) of poly(2-ethyl-2-oxazoline) on ovarian follicle ultrastructure of zebrafish were investigated with light and electron microscopy. After five days of administation, ovary tissues were disected and routine histological processes were done. Severe structural deformation at zona radiata, follicular epithelium and outer granulosa cell structure were observed. Edema at follicular epithelium, zona radiata and vitelline envelope stuructures were detected. Dose dependent increase in the number of immature oocytes were seen. Briefly, it was demonstrated that poly(2-ethyl-2-oxazoline) exposure affected oogenesis and caused apoptosis in zebrafish.
dc.language English
dc.publisher NATL INST SCIENCE COMMUNICATION-NISCAIR
dc.subject Life Sciences & Biomedicine - Other Topics
dc.title Ovarian follicle structure of Zebrafish (Danio rerio Hamilton) after poly(2-ethyl-2-oxazoline) exposure
dc.type Article
dc.identifier.volume 54
dc.identifier.startpage 829
dc.identifier.endpage 834
dc.contributor.department Sakarya Üniversitesi/Fen-Edebiyat Fakültesi/Biyoloji Bölümü
dc.contributor.saüauthor Yön Ertuğ, Nazan Deniz
dc.contributor.saüauthor Olgun, Uğursoy
dc.contributor.saüauthor Akbulut, Cansu
dc.relation.journal INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY
dc.identifier.wos WOS:000389559000005
dc.identifier.eissn 0975-1009
dc.contributor.author Yön Ertuğ, Nazan Deniz
dc.contributor.author Olgun, Uğursoy
dc.contributor.author Akbulut, Cansu


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