Browsing Fen-Edebiyat Fakültesi by Author "Aydan Dag"

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Design, synthesis and docking study of novel coumarin ligands as potential selective acetylcholinesterase inhibitors

Sönmez, Fatih; Belma Zengin Kurt; Isil Gazioglu; Livia Basile; Aydan Dag; Valentina Cappello; Tiziana Ginex; Küçükislamoğlu, Mustafa; Salvatore Guccione (TAYLOR & FRANCIS LTD, 2017)

New coumaryl-thiazole derivatives with the acetamide moiety as a linker between the alkyl chains and/or the heterocycle nucleus were synthesized and in vitro tested as acetylcholinesterase (AChE) inhibitors. 2-(diethylam ...
Synthesis and biological evaluation of novel coumarin-chalcone derivatives containing urea moiety as potential anticancer agents

Belma Zengin Kurt; Nur Ozten Kandas; Aydan Dag; Sönmez, Fatih; Küçükislamoğlu, Mustafa (ELSEVIER, 2020)

The increasing interest on new drug discovery is constantly up to date as drugs do not increase survival adequately against increasing cancer cases worldwide. Based on the reported anticancer activity of coumarin, chalcone ...