Two New Co(II) Complexes of Picolinate: Synthesis, Crystal Structure, Spectral Characterization, -Glucosidase nhibition and TD/DFT Study

Suemeyye Alturk; Avcı, Davut; Belma Zengin Kurt; Tamer, Ömer; Başoğlu, Adil; Fatih Sönmez; Atalay, Yusuf; Necmi Dege

dc.contributor.authors	Alturk, S; Avci, D; Kurt, BZ; Tamer, O; Basoglu, A; Sonmez, F; Atalay, Y; Dege, N;
dc.date.accessioned	2020-01-20T08:02:43Z
dc.date.available	2020-01-20T08:02:43Z
dc.date.issued	2019
dc.identifier.citation	Alturk, S; Avci, D; Kurt, BZ; Tamer, O; Basoglu, A; Sonmez, F; Atalay, Y; Dege, N; (2019). Two New Co(II) Complexes of Picolinate: Synthesis, Crystal Structure, Spectral Characterization, -Glucosidase nhibition and TD/DFT Study. JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS, 29, 1279-1265
dc.identifier.issn	1574-1443
dc.identifier.uri	https://hdl.handle.net/20.500.12619/32314
dc.identifier.uri	https://doi.org/10.1007/s10904-019-01090-7
dc.description.abstract	.
dc.description.abstract	Co(II) complexes of 2-picolinic acid (picH) and 6-methylpyridine-2-carboxylic acid (6-MepicH) {[Co(pic)2·2H2O], (1), [Co(6-Mepic)(pic)·2H2O], (2)} were obtained and their structural and spectroscopic properties were investigated by XRD, FT–IR and UV–Vis spectroscopic techniques. The measurement of α-glucosidase inhibition of the synthesized complex 2 was fulfilled by IC50 values. In order to provide further explanations about the electronic spectral properties, TD–DFT calculations in ethanol solvent and gas phase were carried out. HSEh1PBE/6-311G(d,p) level has been used to calculate the nonlinear optics (NLO) parameters and frontier molecular orbital (FMO) energies. The experimental refractive indexes and optical band gap energies for the Co(II) complexes have been obtained using FT–IR and UV–Vis spectra, respectively. Lastly, the molecular docking study of Co(II) complexes was carried out in order to demonstrate interactions between the synthesized complexes and target protein (the template structure S. cerevisiae isomaltase).
dc.language	English
dc.publisher	SPRINGER
dc.subject	Polymer Science
dc.title	Two New Co(II) Complexes of Picolinate: Synthesis, Crystal Structure, Spectral Characterization, -Glucosidase nhibition and TD/DFT Study
dc.type	Article
dc.identifier.volume	29
dc.identifier.startpage	1265
dc.identifier.endpage	1279
dc.contributor.department	Sakarya Üniversitesi/Fen-Edebiyat Fakültesi/Fizik Bölümü
dc.contributor.saüauthor	Avcı, Davut
dc.contributor.saüauthor	Tamer, Ömer
dc.contributor.saüauthor	Başoğlu, Adil
dc.contributor.saüauthor	Atalay, Yusuf
dc.relation.journal	JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS
dc.identifier.wos	WOS:000471198700022
dc.identifier.doi	10.1007/s10904-019-01090-7
dc.identifier.eissn	1574-1451
dc.contributor.author	Suemeyye Alturk
dc.contributor.author	Avcı, Davut
dc.contributor.author	Belma Zengin Kurt
dc.contributor.author	Tamer, Ömer
dc.contributor.author	Başoğlu, Adil
dc.contributor.author	Fatih Sönmez
dc.contributor.author	Atalay, Yusuf
dc.contributor.author	Necmi Dege