Browsing Kimya / Chemistry by Author "Arleta Rifati Nixha"

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Development of carbazole-bearing pyridopyrimidine-substituted urea/thiourea as polyphenol oxidase inhibitors: synthesis, biochemistry, and theoretical studies

Arleta Rifati Nixha; Adem Ergun; Nahit Gencer; Oktay Arslan; Arslan, Mustafa (TAYLOR & FRANCIS LTD, 2019)

Polyphenol oxidase (Tyrosinase, PPO) has received considerable attention, since it is the key enzyme in melanin biosynthesis. In this study, we investigated prepared novel carbazole-containing pyridopyrimidine-substituted ...
Synthesis and evaluation of N-heteroarylsubstituted triazolosulfonamides as carbonic anhydrase inhibitors

Ahmet Balci; Arslan, Mustafa; Arleta Rifati Nixha; Cigdem Bilen; Adem Ergun; Nahit Gencer (TAYLOR & FRANCIS LTD, 2015)

A new series of N-heteroarylsubstituted triazolosulfonamide compounds were synthesized and their inhibitory effects on the activity of purified human carbonic anhydrase (hCA) I and II were evaluated. Compounds (3 a-k) were ...
Synthesis, biological evaluation and in silico studies of novel N-substituted phthalazine sulfonamide compounds as potent carbonic anhydrase and acetylcholinesterase inhibitors

Cuneyt Turkes; Arslan, Mustafa; Yeliz Demir; Liridon Cocaj; Arleta Rifati Nixha; Sukru Beydemir (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2019)

The synthesis, characterization and biological evaluation of a series of novel N-substituted phthalazine sulfonamide (5a-1) are disclosed. Phthalazines which are nitrogen-containing heterocyclic compounds are biologically ...