- DSpace Home
- →
- Fakülteler / Faculties
- →
- Browsing Fakülteler / Faculties by Author
JavaScript is disabled for your browser. Some features of this site may not work without it.
Browsing Fakülteler / Faculties by Author "Güney Eskiler, Gamze"
Now showing items 1-20 of 30
-
Güney Eskiler, Gamze; G. Cecener; G. Dikmen; I. Kani; U. Egeli; B. Tunca (TAYLOR & FRANCIS, 2016)Manganese (Mn)-based complexes have been drawing attention due to the fact that they are more effective than other metal complexes. However, the use of Mn(II)-based complexes in medicine remains limited because of certain ...
-
Güney Eskiler, Gamze; Gulsah Cecener; Berrin Tunca; Unal Egeli (SPRINGER, 2016)The development of resistance to tamoxifen (Tam) remains a challenging clinical problem for ER+ breast cancer patients. To understand the mechanisms underlying of resistance, previous studies have driven the acquisition ...
-
G. Cecener; Güney Eskiler, Gamze; Güney Eskiler, Gamze; U. Egeli; B. Tunca; A. Alemdar; S. Gokgoz; I. Tasdelen (SPRINGER, 2016)
-
Güney Eskiler, Gamze; Güney Eskiler, Gamze; Gulsah Cecener; Unal Egeli; Berrin Tunca (WILEY, 2019)The objective of the present study was to elucidate the effect of BMN 673 (talozoparib) on BRCA1 mutant (HCC1937) and wild-type (MDA-MB-231) triple negative breast cancer (TNBC). The in vitro cytotoxicity results indicated ...
-
Güney Eskiler, Gamze; Şahin, Elvan; Deveci Özkan, Asuman; Kaleli, Süleyman (ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 2019)Curcumin has a therapeutic potential activity through modulation of different signaling pathways in various types of cancer. However, the relationship between the efficacy of curcumin and the homologous recombination (HR) ...
-
Güney Eskiler, Gamze; Gulsah Cecener; Unal Egeli; Berrin Tunca (IEEE, 2017)The anti-estrogen tamoxifen (Tam) is the most preferred option for patients with estrogen-receptor (ER)-positive breast cancer. However, multi-drug resistance (MDR) is a considerable clinical problem in the successful ...
-
Isil Ezgi Eryilmaz; Güney Eskiler, Gamze; Gulsah Cecener; Unal Egeli; Berrin Tunca (IEEE, 2017)We mentioned the importance of clinical sequence analysis in risk determination, diagnostic and therapeutic process of familial breast cancer and we also summarized next generation sequencing applications in this cancer ...
-
Guney G. Eskiler; Güney Eskiler, Gamze; E. Bezdegumeli; Z. Ozman; Deveci A. Ozkan; Deveci Özkan, Asuman; Bilir, Cemil; Bilir, Cemil; B. N. Kucukakca; M. N. Ince; A. Y. Men; O. Aktas; Y. E. Horoz; D. Akpinar (COMENIUS UNIV, 2019)CONCLUSION: STAT3 may be considered as a therapeutic target for cachectic patients with gastric, lung and breast cancer. Furthermore, IL-6 mediates STAT3 activation in cachectic gastric and breast cancer patients (Tab. 5, ...
-
Guney G. Eskiler; Güney Eskiler, Gamze; E. Bezdegumeli; Z. Ozman; Deveci A. Ozkan; Deveci Özkan, Asuman; Bilir, Cemil; Bilir, Cemil; B. N. Kucukakca; M. N. Ince; A. Y. Men; O. Aktas; Y. E. Horoz; D. Akpinar (COMENIUS UNIV, 2019)CONCLUSION: STAT3 may be considered as a therapeutic target for cachectic patients with gastric, lung and breast cancer. Furthermore, IL-6 mediates STAT3 activation in cachectic gastric and breast cancer patients (Tab. 5, ...
-
Güney Eskiler, Gamze; Ibrahim Kani (WALTER DE GRUYTER GMBH, 2019)Conclusions: Zn(II) complex has great therapeutic potential for the treatment of breast cancer. However, further studies are warranted to identify the underlying mechanisms of apoptotic cell death and to reduce the toxicity ...
-
Isil Ezgi Eryilmaz; Güney Eskiler, Gamze; Unal Egeli; Beste Yurdacan; Gulsah Cecener; Berrin Tunca (WILEY, 2018)The aim of the current study was first to investigate cytotoxic activity of usnic acid (UA) on hormone-dependent breast and prostate cancer, and normal cells. Cells were treated with increasing concentrations (25 to 150 ...
-
Güney Eskiler, Gamze; Deveci Özkan, Asuman; Kaleli, Süleyman; Bilir, Cemil (CANADIAN SOC PHARMACEUTICAL SCIENCES, 2019)Purpose: Toll-like receptor 4 (TLR4) is over-expressed in breast tumors and thus contributing to the tumor progression and metastasis. Natural products have drawn attention in cancer immunotherapy due to their various ...
-
Güney Eskiler, Gamze; Deveci Özkan, Asuman; Kaleli, Süleyman; Bilir, Cemil (CANADIAN SOC PHARMACEUTICAL SCIENCES, 2019)Purpose: Toll-like receptor 4 (TLR4) is over-expressed in breast tumors and thus contributing to the tumor progression and metastasis. Natural products have drawn attention in cancer immunotherapy due to their various ...
-
Beste Yurdacan; Unal Egeli; Güney Eskiler, Gamze; Güney Eskiler, Gamze; Isil Ezgi Eryilmaz; Gulsah Cecener; Berrin Tunca (WILEY, 2019)Objectives Sorafenib (SOR) is an orally administered molecular targeted agent in the systemic chemotherapy of hepatocellular carcinoma (HCC). However, the partial response of SOR is limited due to its adverse side effect ...
-
Gulsah Cecener; Güney Eskiler, Gamze; Unal Egeli; Berrin Tunca (ELSEVIER SCIENCE BV, 2017)
-
Güney Eskiler, Gamze (ELSEVIER SCIENCE BV, 2018)The objective of the present study was to investigate the effect of tamoxifen (Tam) loaded solid lipid nano-particles (SLNs) on MCF7 Tam-resistant breast cancer cells (MCF7-TamR). Tam-SLNs were produced by the hot ...
-
Güney Eskiler, Gamze; Güney Eskiler, Gamze; Isil Ezgi Eryilmaz; Beste Yurdacan; Unal Egeli; Gulsah Cecener; Berrin Tunca (WILEY, 2019)The aim of this study was to investigate the combined effects of usnic acid (UA) and Tamoxifen (Tam) or Enzalutamide (Enz) on hormone receptor-positive breast and prostate cancer (BC and PC), respectively. The antiproliferative ...
-
Güney Eskiler, Gamze; Deveci Özkan, Asuman; Bilir, Cemil; Kaleli, Süleyman (ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 2019)Objective: Herein we, for the first time, investigated a potential synergistic effect of nobiletin (NOB) and sorafenib (SOR) on PC-3 prostate cancer and HUVEC control cell lines.Methods: In order to determine the cytotoxic ...
-
Güney Eskiler, Gamze; Deveci Özkan, Asuman; Bilir, Cemil; Kaleli, Süleyman (ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 2019)Objective: Herein we, for the first time, investigated a potential synergistic effect of nobiletin (NOB) and sorafenib (SOR) on PC-3 prostate cancer and HUVEC control cell lines.Methods: In order to determine the cytotoxic ...
-
Güney Eskiler, Gamze; Gulsah Cecener; Unal Egeli; Berrin Tunca (SPRINGER/PLENUM PUBLISHERS, 2018)PurposeThe purpose of the study was to produce BMN 673 loaded solid lipid nanoparticles (SLNs) to improve its therapeutic index, to minimize toxicity and to overcome homologous recombination (HR)-mediated resistance.Meth ...
Now showing items 1-20 of 30
Browse
-
All of DSpace
-
This Community
My Account
Sakarya Üniversitesi Esentepe Yerleşkesi, 54054 - Serdivan, Sakarya, TURKEY
If you find any errors in content, please contact: dspace@sakarya.edu.tr
DSpace@Sakarya by Sakarya University Institutional Repository is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 Unported License..
DSpace@Sakarya:
