dc.date.accessioned |
2021-06-03T11:02:27Z |
|
dc.date.available |
2021-06-03T11:02:27Z |
|
dc.date.issued |
2021 |
|
dc.identifier.issn |
1300-0144 |
|
dc.identifier.uri |
https://www.doi.org/10.3906/sag-2007-59 |
|
dc.identifier.uri |
https://hdl.handle.net/20.500.12619/95507 |
|
dc.description |
Bu yayın 06.11.1981 tarihli ve 17506 sayılı Resmî Gazete’de yayımlanan 2547 sayılı Yükseköğretim Kanunu’nun 4/c, 12/c, 42/c ve 42/d maddelerine dayalı 12/12/2019 tarih, 543 sayılı ve 05 numaralı Üniversite Senato Kararı ile hazırlanan Sakarya Üniversitesi Açık Bilim ve Açık Akademik Arşiv Yönergesi gereğince açık akademik arşiv sistemine açık erişim olarak yüklenmiştir. |
|
dc.description |
Bu yayın 06.11.1981 tarihli ve 17506 sayılı Resmî Gazete’de yayımlanan 2547 sayılı Yükseköğretim Kanunu’nun 4/c, 12/c, 42/c ve 42/d maddelerine dayalı 12/12/2019 tarih, 543 sayılı ve 05 numaralı Üniversite Senato Kararı ile hazırlanan Sakarya Üniversitesi Açık Bilim ve Açık Akademik Arşiv Yönergesi gereğince açık akademik arşiv sistemine açık erişim olarak yüklenmiştir. |
|
dc.description.abstract |
Background/aim: In this study, we aim to investigate the efficacy of convalescent plasma (CP) according to blood groups (BGs) in the treatment of critically ill patients diagnosed with COVID-19. Materials and methods: Twenty-eight critically ill and laboratory-confirmed COVID-19 patients who were admitted to the intensive care unit (ICU) of Sakarya University, Medical Faculty were included in the study. Patients were divided into 2 groups: patients who received anti-A antibody (Ab) containing CP (BG O and B) and those who did not receive CP containing anti-A Ab (BG A and AB). Results: Among the 28 patients, 13 patients received anti-A Ab containing CP (BG; B: 6, O: 7) and 15 patients did not receive anti-A Ab CP (BG; A: 13, AB: 2). Duration in ICU, the rates of mechanical ventilation (MV) support and vasopressor support, the case fatality rate, and the discharge rate were lower in patients who received CP containing anti-A Ab than not containing anti-A Ab CP. However, only the difference in the rate of MV support achieved statistically significance (P = 0.04) Conclusion: In our study, it was observed that the efficiency of CP without anti-A antibody was lower than that of plasma containing anti-A antibody, although it was not statistically significant. This result is thought to be due to the anti-A antibody's ability to block the ACE2 receptor. We believe that this hypothesis should be investigated in controlled studies with higher patient numbers. |
|
dc.language |
English |
|
dc.language.iso |
eng |
|
dc.publisher |
TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY |
|
dc.relation.isversionof |
10.3906/sag-2007-59 |
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dc.rights |
info:eu-repo/semantics/openAccess |
|
dc.subject |
Blood groups |
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dc.subject |
COVID-19 |
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dc.subject |
convalescent plasma |
|
dc.title |
Efficacy of convalescent plasma according to blood groups in COVID-19 patients |
|
dc.type |
Article |
|
dc.contributor.authorID |
Sunu, Cenk/0000-0002-6513-6211 |
|
dc.contributor.authorID |
GENC, AHMED CIHAD/0000-0002-7725-707X |
|
dc.contributor.authorID |
KARABAY, OGUZ/0000-0003-1514-1685 |
|
dc.contributor.authorID |
hacibekiroglu, ilhan/0000-0002-0333-7405 |
|
dc.identifier.volume |
51 |
|
dc.identifier.startpage |
45 |
|
dc.identifier.endpage |
48 |
|
dc.relation.journal |
TURKISH JOURNAL OF MEDICAL SCIENCES |
|
dc.identifier.issue |
1 |
|
dc.identifier.wos |
WOS:000623196400006 |
|
dc.identifier.doi |
10.3906/sag-2007-59 |
|
dc.identifier.eissn |
1303-6165 |
|
dc.contributor.author |
Hacibekiroglu, Tuba |
|
dc.contributor.author |
Kalpakci, Yasin |
|
dc.contributor.author |
Genc, Ahmet Cihat |
|
dc.contributor.author |
Hacibekiroglu, Ilhan |
|
dc.contributor.author |
Sunu, Cenk |
|
dc.contributor.author |
Saricaoglu, Adem |
|
dc.contributor.author |
Tomak, Yakuo |
|
dc.contributor.author |
Karabay, Oguz |
|
dc.contributor.author |
Koroglu, Mehmet |
|
dc.relation.publicationcategory |
Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı |
|
dc.identifier.pmıd |
32950044 |
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dc.rights.openaccessdesignations |
Green Published, Bronze |
|