dc.rights.license |
DOAJ Gold |
|
dc.date.accessioned |
2021-06-03T08:20:17Z |
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dc.date.available |
2021-06-03T08:20:17Z |
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dc.date.issued |
2020 |
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dc.identifier.uri |
www.doi.org/10.1590/1806-9282.66.6.746 |
|
dc.identifier.uri |
https://hdl.handle.net/20.500.12619/95122 |
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dc.description |
Bu yayın 06.11.1981 tarihli ve 17506 sayılı Resmî Gazete’de yayımlanan 2547 sayılı Yükseköğretim Kanunu’nun 4/c, 12/c, 42/c ve 42/d maddelerine dayalı 12/12/2019 tarih, 543 sayılı ve 05 numaralı Üniversite Senato Kararı ile hazırlanan Sakarya Üniversitesi Açık Bilim ve Açık Akademik Arşiv Yönergesi gereğince açık akademik arşiv sistemine açık erişim olarak yüklenmiştir. |
|
dc.description.abstract |
OBJECTIVE: The present study aimed to investigate the role of neutrophil/lymphocyte ratio (NLR), an inflammation marker, complete blood count, and biochemical parameters in the diagnosis of COVID-19. METHODS: A total of 80 patients who had been hospitalized in the internal medicine clinic were enrolled in the study. The cases were allocated into two groups, i.e., COVID (+) and (-), based on real-time reverse transcription-polymerase chain reaction. The demographic, clinical, and laboratory [NLR, platelet/lymphocyte ratio (PLR), complete blood count, biochemistry, and serology] data of the patients were retrospectively obtained from the hospital data management system. RESULTS: NLR and fever levels were found to be higher in COVID-19 (+) cases (P=0.021, P=0.001, respectively). There was no difference between males and females with regard to COVID-19 positivity (P=0.527). Total bilirubin levels were found to be lower in COVID-19 (+) cases (P=0.040). When the ROC analysis was carried out for NLR in COVID-19 (+) cases, the AUC value was found to be 0.660 (P=0.021), sensitivity as 69.01 %, specificity as 65.40 %, LR+: 1.98 and LR- : 0.48, PPV: 80.43, and NPV: 50.00, when the NLR was >= 2.4. The risk of COVID-19 was found to be 20.3-fold greater when NLR was >= 2.4 in the logistic regression (P=0.007). CONCLUSION: NLR is an independent predictor for the diagnosis of COVID-19. We also found that fever and total bilirubin measurements could be useful for the diagnosis of COVID-19 in this population. |
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dc.language |
English |
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dc.language.iso |
İngilizce |
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dc.publisher |
ASSOC MEDICA BRASILEIRA |
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dc.relation.isversionof |
10.1590/1806-9282.66.6.746 |
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dc.rights |
info:eu-repo/semantics/openAccess |
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dc.subject |
PNEUMONIA |
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dc.subject |
Coronavirus Infections |
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dc.subject |
Coronavirus |
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dc.subject |
Fever |
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dc.subject |
Lymphocytes |
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dc.subject |
Neutrophils |
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dc.title |
Can the neutrophil/lymphocyte ratio (NLR) have a role in the diagnosis of coronavirus 2019 disease (COVID-19)? |
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dc.type |
Article |
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dc.contributor.authorID |
Kaya, Tezcan/0000-0003-0483-2333 |
|
dc.contributor.authorID |
YAYLACI, SELCUK/0000-0002-6768-7973 |
|
dc.contributor.authorID |
Varim, Ceyhun/0000-0002-8369-0857 |
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dc.identifier.volume |
66 |
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dc.identifier.startpage |
746 |
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dc.identifier.endpage |
751 |
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dc.relation.journal |
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA |
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dc.identifier.issue |
6 |
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dc.identifier.wos |
WOS:000551893100010 |
|
dc.identifier.doi |
10.1590/1806-9282.66.6.746 |
|
dc.identifier.eissn |
1806-9282 |
|
dc.contributor.author |
Nalbant, Ahmet |
|
dc.contributor.author |
Kaya, Tezcan |
|
dc.contributor.author |
Varim, Ceyhun |
|
dc.contributor.author |
Yaylaci, Selcuk |
|
dc.contributor.author |
Tamer, Ali |
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dc.contributor.author |
Cinemre, Hakan |
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dc.relation.publicationcategory |
Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı |
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dc.identifier.pmıd |
32696861 |
|