Browsing Araştırma Çıktıları / Research Outputs by Subject "15-Lipoxygenase"

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Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis

Anthonymuthu, Tamil S.; Tyurina, Yulia Y.; Sun, Wan-Yang; Mikulska-Ruminska, Karolina; Shrivastava, Indira H.; Tyurin, Vladimir A.; Cinemre, Fatma B.; Dar, Haider H.; VanDemark, Andrew P. (ELSEVIER, 2021)

Hydroperoxy-eicosatetraenoyl-phosphatidylethanolamine (HpETE-PE) is a fermptotic cell death signal. HpETE-PE is produced by the 15-Lipoxygenase (15LOX)/Phosphatidylethanolamine Binding Protein-1 (PEBP1) complex or via an ...