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Browsing WOS İndeksli Yayınlar Koleksiyonu / WOS Indexed Publications Collection by Author

Browsing WOS İndeksli Yayınlar Koleksiyonu / WOS Indexed Publications Collection by Author "Turkes, Cuneyt"

Now showing items 1-7 of 7

Cytotoxic effect, enzyme inhibition, and in silico studies of some novel N-substituted sulfonyl amides incorporating 1,3,4-oxadiazol structural motif

Gulec, Ozcan; Turkes, Cuneyt; Arslan, Mustafa; Demir, Yeliz; Yeni, Yesim; Hacimuftuoglu, Ahmet; Ereminsoy, Ergun; Kufrevioglu, Omer Irfan; Beydemir, Sukru (SPRINGER, 2022)

The acetylcholinesterase and carbonic anhydrase inhibitors (AChEIs and hCAIs) remain key therapeutic agents for many bioactivities such as anti-Alzheimer and antiobesity antiepileptic, anticancer, antiinfective, antiglaucoma, ...
Discovery of novel benzenesulfonamides incorporating 1,2,3-triazole scaffold as carbonic anhydrase I, II, IX, and XII inhibitors

Buza, Aida; Turkes, Cuneyt; Arslan, Mustafa; Demir, Yeliz; Dincer, Busra; Nixha, Arleta Rifati; Beydemir, Sukru (2023)

Sulfonamides are among the most promising potential inhibitors for carbonic anhydrases (CAs), which are pharmaceutically relevant targets for treating several disease conditions. Herein, a series of benzenesulfonamides ...
N-substituted phthalazine sulfonamide derivatives as non-classical aldose reductase inhibitors

Turkes, Cuneyt; Arslan, Mustafa; Demir, Yeliz; Cocaj, Liridon; Nixha, Arleta Rifati; Beydemir, Sukru (2022)

Aldose reductase (AR, AKR1B1; EC 1.1.1.21) is an aldo-keto reductase that has been widely investigated as an enzyme crucially involved in the pathogenesis of several chronic complications, including nephropathy, neuropathy, ...
Novel benzoic acid derivatives: Synthesis and biological evaluation as multitarget acetylcholinesterase and carbonic anhydrase inhibitors

Kalayci, Muharrem; Turkes, Cuneyt; Arslan, Mustafa; Demir, Yeliz; Beydemir, Sukru (WILEY-V C H VERLAG GMBH, 2021)

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by dementia, memory impairment, cognitive dysfunction, and speech impairment. The utility of cholinergic replacement by acetylcholinesterase (AChE) ...
Novel beta-lactam substituted benzenesulfonamides: in vitro enzyme inhibition, cytotoxic activity and in silico interactions

Gulec, Ozcan; Turkes, Cuneyt; Arslan, Mustafa; Demir, Yeliz; Dincer, Busra; Ece, Abdulilah; Beydemir, Sukru (TAYLOR & FRANCIS INC, 2023)

In this study, a library of twelve beta-lactam-substituted benzenesulfonamides (5a-l) was synthesized using the tail-approach method. The compounds were characterized using IR, H-1 NMR, C-13 NMR and elemental analysis ...
Sulfonamides incorporating ketene N,S-acetal bioisosteres as potent carbonic anhydrase and acetylcholinesterase inhibitors

Istrefi, Qendresa; Turkes, Cuneyt; Arslan, Mustafa; Demir, Yeliz; Nixha, Arleta R.; Beydemir, Sukru; Kufrevioglu, Omer, I (WILEY-V C H VERLAG GMBH, 2020)

In this study, 15 novel compounds in a series of sulfonamide-based ketenes (7a-o) were synthesized and characterized using Fourier-transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, and mass spectrometry. ...
Synthesis, characterisation, biological evaluation and in silico studies of sulphonamide Schiff bases

Durgun, Mustafa; Turkes, Cuneyt; Isik, Mesut; Demir, Yeliz; Sakli, Ali; Kuru, Ali; Guzel, Abdussamat; Beydemir, Sukru; Akocak, Suleyman; Osman, Sameh M.; AlOthman, Zeid; Supuran, Claudiu T. (TAYLOR & FRANCIS LTD, 2020)

Sulphonamides are biologically important compounds with low toxicity, many bioactivities and cost-effectiveness. Eight sulphonamide derivatives were synthesised and characterised by FT-IR, C-13 NMR, H-1 NMR, LC-MS and ...