Browsing by Subject "TARGET"

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Evaluation of the Effects of Nobiletin on Toll-Like Receptor 3 Signaling Pathways in Prostate Cancer In Vitro

Ozkan, Asuman Deveci; Sarihan, Mehmet; Kaleli, Suleyman (ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, )

Nobiletin as a nontoxic dietary citrus flavonoid has anticancer effects in cancer. Toll-like receptor three has a role in prostate cancer progression. However the relationship among NOB and TLR3 signaling in PCa has not ...
Long noncoding RNA ERICD interacts with ARID3A via E2F1 and regulates migration and proliferation of osteosarcoma cells

Arman, Kaifee; Saadat, Khandakar A. S. M.; Igci, Yusuf Z.; Bozgeyik, Esra; Ikeda, Masa-Aki; Cakmak, Ecir A.; Arslan, Ahmet (WILEY, 2020)

Long noncoding RNA (lncRNA) dysregulation is known to be taking part in majority of cancers, including osteosarcoma. In one of our previous studies, we showed that lncRNA MEG3 is being regulated by microRNA-664a (miR-664a) ...
The suppression of ATR/Chk1 pathway by Elimusertib ATR inhibitor in triple negative breast cancer cells

Haciefendi, A; Eskiler, GG (2023)

Objectives: Genomic instability in cancer cells is based on the aberrant activation of deoxyribonucleic acid (DNA) damage response and repair mechanisms. Targeting Ataxia telangiectasia and Rad3-related (ATR) inhibition ...