Browsing by Subject "Benzenesulfonamide"

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Discovery of novel benzenesulfonamides incorporating 1,2,3-triazole scaffold as carbonic anhydrase I, II, IX, and XII inhibitors

Buza A.; Türkeş C.; Arslan M.; Demir Y.; Dincer B.; Nixha A.R.; Beydemir S. (2023)

Sulfonamides are among the most promising potential inhibitors for carbonic anhydrases (CAs), which are pharmaceutically relevant targets for treating several disease conditions. Herein, a series of benzenesulfonamides ...
Exploration of 1,2,3-triazole linked benzenesulfonamide derivatives as isoform selective inhibitors of human carbonic anhydrase

Kakakhan C.; Türkeş C.; Güleç Ö.; Demir Y.; Arslan M.; Özkemahlı G.; Beydemir (2023)

A novel series of 1,2,3-triazole benzenesulfonamide substituted 1,3-dioxoisoindolin-5-carboxylate (7a-l) inhibitors of human ?-carbonic anhydrase (hCA) was designed using a tail approach. The design method relies on the ...