Browsing by Author "Yanar, Sevinc"

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Investigation of the effect of meclofenamic acid on the proteome of LNCaP cells reveals changes in alternative polyadenylation and splicing machinery

Saglam, Busra Sahinoz; Kanli, Aylin; Yanar, Sevinc; Kasap, Murat; Akpinar, Gurler (2022)

Prostate cancer is the most common type of cancer among men, and there is still no definitively effective drug treatment. Thus, the search for novel drug agents that may be used for the effective treatment continues. ...
Proteomic analysis of talazoparib resistance in triple-negative breast cancer cells

Guney Eskiler, Gamze; Yanar, Sevinc; Akpinar, Gurler; Kasap, Murat (WILEY, 2021)

Talazoparib (TAL) has been effectively used for the treatment of gBRCA1/2-mutated HER2-negative metastatic breast cancer. However, acquired resistance to TAL remains a major challenge that impedes the clinical success of ...