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Browsing by Author "Turkes, Cuneyt/0000-0002-2932-2789"

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Novel benzoic acid derivatives: Synthesis and biological evaluation as multitarget acetylcholinesterase and carbonic anhydrase inhibitors

Kalayci, Muharrem; Turkes, Cuneyt; Arslan, Mustafa; Demir, Yeliz; Beydemir, Sukru (WILEY-V C H VERLAG GMBH, 2021)

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by dementia, memory impairment, cognitive dysfunction, and speech impairment. The utility of cholinergic replacement by acetylcholinesterase (AChE) ...
Sulfonamides incorporating ketene N,S-acetal bioisosteres as potent carbonic anhydrase and acetylcholinesterase inhibitors

Istrefi, Qendresa; Turkes, Cuneyt; Arslan, Mustafa; Demir, Yeliz; Nixha, Arleta R.; Beydemir, Sukru; Kufrevioglu, Omer, I (WILEY-V C H VERLAG GMBH, 2020)

In this study, 15 novel compounds in a series of sulfonamide-based ketenes (7a-o) were synthesized and characterized using Fourier-transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, and mass spectrometry. ...
Synthesis, characterisation, biological evaluation and in silico studies of sulphonamide Schiff bases

Durgun, Mustafa; Turkes, Cuneyt; Isik, Mesut; Demir, Yeliz; Sakli, Ali; Kuru, Ali; Guzel, Abdussamat; Beydemir, Sukru; Akocak, Suleyman; Osman, Sameh M.; AlOthman, Zeid; Supuran, Claudiu T. (TAYLOR & FRANCIS LTD, 2020)

Sulphonamides are biologically important compounds with low toxicity, many bioactivities and cost-effectiveness. Eight sulphonamide derivatives were synthesised and characterised by FT-IR, C-13 NMR, H-1 NMR, LC-MS and ...