Browsing by Author "Nixha, Arleta Rifati"

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Discovery of novel benzenesulfonamides incorporating 1,2,3-triazole scaffold as carbonic anhydrase I, II, IX, and XII inhibitors

Buza, Aida; Turkes, Cuneyt; Arslan, Mustafa; Demir, Yeliz; Dincer, Busra; Nixha, Arleta Rifati; Beydemir, Sukru (2023)

Sulfonamides are among the most promising potential inhibitors for carbonic anhydrases (CAs), which are pharmaceutically relevant targets for treating several disease conditions. Herein, a series of benzenesulfonamides ...
N-substituted phthalazine sulfonamide derivatives as non-classical aldose reductase inhibitors

Turkes, Cuneyt; Arslan, Mustafa; Demir, Yeliz; Cocaj, Liridon; Nixha, Arleta Rifati; Beydemir, Sukru (2022)

Aldose reductase (AR, AKR1B1; EC 1.1.1.21) is an aldo-keto reductase that has been widely investigated as an enzyme crucially involved in the pathogenesis of several chronic complications, including nephropathy, neuropathy, ...